Clinical Trials Logo

Transfusion Related Complication clinical trials

View clinical trials related to Transfusion Related Complication.

Filter by:
  • Not yet recruiting  
  • Page 1

NCT ID: NCT06399536 Not yet recruiting - Clinical trials for Transfusion Related Complication

Individualized ANH for Non-cardiac Surgery

Start date: June 1, 2024
Phase: N/A
Study type: Interventional

In this trial, we proposed an individualized acute normovolemic hemodilution (ANH), and conduct a randomized controlled trial to testify the effect of individualized ANH on red cells requirement for non-cardiac surgeries with anticipating major blood loss in adults.

NCT ID: NCT05696210 Not yet recruiting - Clinical trials for Extracorporeal Membrane Oxygenation Complication

Evaluation of the 1-year Prognosis of Patients Under Veno-arterial Extracorporeal Membrane Oxygenation for Cardiogenic Shock With Blood Transfusion Requirement

HemoECMO
Start date: January 20, 2023
Phase:
Study type: Observational

The primary objective of this work is to study the 1-year prognosis of patients who received Veno-arterial extracorporeal membrane oxygenation for cardiogenic shock with the need for blood transfusion. Secondary objectives are to determine whether the transfusion strategy used (liberal or restrictive) still has an impact on overall mortality. We will also determine the factors associated with overall in-hospital mortality and look at the impact of transfusion in relation to the risk of hemolysis on the consequences in the occurrence of long-term chronic renal failure.

NCT ID: NCT04413721 Not yet recruiting - Clinical trials for Transfusion Related Complication

Effects of Packed Red Blood Cell Storage Duration on Pediatric Living Donor Liver Transplantation

Start date: July 1, 2020
Phase: N/A
Study type: Interventional

The patients assigned to either short-storage leukoreduced RBCs group (stored for ≤ 14 days) or longer-term storage leukoreduced RBCs group(stored for ≥21 days).When the hemoglobin concentration fell below 7.0 g per deciliter, PRBC were given to maintain the hemoglobin concentrations in the range of 7.0 to 10.0/dL. The primary outcome : Death from all causes in1-year after randomization. Secondary outcomes included: Intraoperative blood transfusion, Postoperative blood transfusion, Postoperative inflammatory reaction, Mechanical ventilation time in the intensive care unit, Lengths of stay in the intensive care unit and the hospital were also recorded.

NCT ID: NCT03934112 Not yet recruiting - Clinical trials for Transfusion Related Complication

Impact of Transfusional Practice on the Morbidity and Mortality of Patients in Intensive Care Unit

PATMORE
Start date: June 2019
Phase:
Study type: Observational

This study will allow correlating transfusion monitoring and patients' prognostic according to the chosen outcome criteria. These data could thus represent a basis for transfusion recommendations, except for intensive care and vital emergencies. It will also bring information about the actual transfusion monitoring in intensive care unit (ICU), in the period following the stay in the ICU and after hospital discharge.

NCT ID: NCT02587845 Not yet recruiting - Bleeding Clinical Trials

Use of Transexamic Acid in Hip Replacement

Start date: October 2015
Phase: Phase 3
Study type: Interventional

Studies have shown that tranexamic acid reduces blood loss and transfusion need in patients undergoing total hip arthroplasty. However, no to date, no study has been large enough to determine definitively whether the drug is safe and effective. The present study was designed to verify noninferior efficacy and safety of topical intra-articular TXA compared with intravenous TXA in primary THA.

NCT ID: NCT02139995 Not yet recruiting - Critical Illness Clinical Trials

West-China Transfusion Score for Critically-ill Patients

Start date: May 2014
Phase: Phase 3
Study type: Interventional

Guidelines for blood transfusion have been issued for years. According to these guidelines, red blood cells (RBCs) transfusion should be given when the hemoglobin level is less than 6g/dL or 7g/dL and is unnecessary when the level is more than 10g/dL. However, in all the guidelines, the determination of whether RBCs should be administered when the hemoglobin level is in the range of 6~10g/dL is based on the judgment from doctors. Index of transfusion trigger for patients with hemoglobin level between 6g/dL and 10g/dL is necessary and important in clinical practice. Based on the aim of blood transfusion that maintain the balance of oxygen supply and oxygen consumption, the investigators hypothesize that index of transfusion trigger for patients with hemoglobin level between 6g/dL and 10g/dL could be calculated by parameters including infusion rate of inotropic drugs for maintaining normal cardiac output, fraction of inspired oxygen, core temperature, and torlerance to anemia. To verify this hypothesis, the investigators present West China Transfusion Score for Critically-ill Patients(WCTS-CP) for the trigger of transfusion according to the patient's history and monitoring parameters, and the investigators design a randomized controlled clinical trial to test this score.