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Clinical Trial Summary

In this study, we planned to identify transcriptome expression profiles (circRNAs, lncRNAs, and mRNAs) from peripheral blood mononuclear cells (PBMCs) of 30 patients with OPLL and 30 other non-OPLL patients by high-throughput sequencing.Sequence analysis was used to predict miRNAs that might bind circRNAs and lncRNAs.Through bioinformatics analysis, competitive endogenous RNAs (cerRNAs), as well as coexpression networks among circRNAs, lncRNAs, miRNAs, and mRNAs, were constructed to provide key molecules and signaling pathways associated with OPLL.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT04963101
Study type Observational
Source Fifth Affiliated Hospital, Sun Yat-Sen University
Contact Ning Jiang, M.D
Phone +86 15653868023
Email jiangn57@mail2.sysu.edu.cn
Status Recruiting
Phase
Start date June 25, 2021
Completion date June 30, 2022

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