Dose Effect of Tranexamic Acid on the Incidence of Deep Venous Thrombus in Cardiac Surgery

Tranexamic Acid Adverse Reaction Clinical Trial

Official title:
Dose Effect of Tranexamic Acid on the Incidence of Deep Venous Thrombus in Cardiac Surgery With Cardiopulmonary Bypass

Status Not yet recruiting

Clinical Trial Summary

In recent years, the lysine analogs tranexamic acid (TXA) has gained wide use in cardiac surgery as a blood-sparing agent. However, the safety of the drug and its impact on overall outcomes of cardiac surgery remains debated. The current study evaluates the dose effect of TXA on the incidence of deep venous thrombus (DVT) in cardiac surgery with cardiopulmonary bypass. Also, the dose effect of TXA on bleeding and allogeneic transfusion is evaluated.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03838328
Study type	Interventional
Source	Chinese Academy of Medical Sciences, Fuwai Hospital
Contact	Jia Shi, M.D.
Phone	86 10 88322467
Email	shiandypumc@sina.com
Status	Not yet recruiting
Phase	Phase 4
Start date	March 1, 2019
Completion date	March 31, 2020

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