Trachoma Clinical Trial
Official title:
Strategies for the Control of Blinding Trachoma: Effect of Fly Spray
The purpose of this community-based randomized trial was to determine, in trachoma hyper-endemic communities of Tanzania, the added value of intensive spraying to control flies on the fly population and on trachoma and ocular chlamydia infection at 6 months and one year after mass antibiotic treatment.
Status | Completed |
Enrollment | 350 |
Est. completion date | October 2002 |
Est. primary completion date | September 2002 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | Both |
Age group | 12 Months to 8 Years |
Eligibility |
Inclusion Criteria: - Balozi in Chiwe area - Sentinel children: age less than 8 years Exclusion Criteria: - Balozi in Chiwe without geographic borders - Sentinel children:age more than 8 years |
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Outcomes Assessor), Primary Purpose: Prevention
Country | Name | City | State |
---|---|---|---|
United States | Johns Hopkins University/ Kongwa Trachoma Project | Baltimore | Maryland |
Lead Sponsor | Collaborator |
---|---|
Johns Hopkins University | Wellcome Trust |
United States,
West SK, Emerson PM, Mkocha H, McHiwa W, Munoz B, Bailey R, Mabey D. Intensive insecticide spraying for fly control after mass antibiotic treatment for trachoma in a hyperendemic setting: a randomised trial. Lancet. 2006 Aug 12;368(9535):596-600. — View Citation
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | clinical trachoma | clinical grading of conjunctival photographs for follicular trachoma | 1 year | No |
Secondary | ocular C. trachomatis infection | laboratory assessment of chlamydial DNA on ocular swab; measured as present or absent | 6 months | No |
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT03676140 -
Safety of Co-administration of IDA and Azithromycin for NTDs ( ComboNTDs )
|
Phase 3 | |
Completed |
NCT01949454 -
Fluorometholone as Ancillary Therapy for TT Surgery
|
N/A | |
Completed |
NCT01202331 -
Tripartite International Research for the Elimination of Trachoma
|
Phase 4 | |
Completed |
NCT05634759 -
Enhancing the A in SAFE for Trachoma
|
Phase 4 | |
Recruiting |
NCT04185402 -
Azithromycin Reduction to Reach Elimination of Trachoma
|
Phase 4 | |
Active, not recruiting |
NCT00886015 -
Modified Instrumentation for Surgery to Correct Trichiasis
|
Phase 3 | |
Completed |
NCT00792922 -
Partnership for Rapid Elimination of Trachoma
|
Phase 4 | |
Completed |
NCT00522860 -
A Trial of Non-absorbable Versus Absorbable Sutures for Trichiasis Surgery
|
Phase 4 | |
Completed |
NCT00221364 -
Trachoma Elimination Follow-up
|
Phase 4 | |
Completed |
NCT00322972 -
Trachoma Amelioration in Northern Amhara (TANA)
|
Phase 4 | |
Withdrawn |
NCT00286026 -
Azithromycin in Control of Trachoma II
|
Phase 4 | |
Terminated |
NCT03997487 -
Smartphone App for Taking Images of Conjunctivae
|
N/A | |
Terminated |
NCT04002726 -
App-based Versus Slide-based Inter-grader Agreement (IGA) Test for Trachoma Graders
|
N/A | |
Not yet recruiting |
NCT06289647 -
Azithromycin Reduction to Reach Elimination of Trachoma B
|
Phase 4 | |
Withdrawn |
NCT02655432 -
Performance of a Photoscreener for Vision Screening in a Haitian Pediatric Population
|
Phase 0 | |
Completed |
NCT01767506 -
A Surveillance and Azithromycin Treatment for Newcomers and Travelers Evaluation: The ASANTE Trial
|
N/A | |
Completed |
NCT00618449 -
Impact of Two Alternative Dosing Strategies for Trachoma Control in Niger
|
Phase 4 | |
Completed |
NCT00356720 -
Efficacy and Safety of 2 Dosing Regimens of T1225 Eye Drops 1.5% Versus Oral Azithromycin in Treatment of Trachoma
|
Phase 3 | |
Completed |
NCT03813069 -
Testing Insect Repellents Against Musca Sorbens, the Vector of Trachoma
|
Phase 2 | |
Recruiting |
NCT03335072 -
Kebele Elimination of Trachoma for Ocular Health
|
Phase 4 |