Treatment of Laryngotracheal Stenosis Using Mesenchymal Stem Cells

Status Enrolling by invitation

Clinical Trial Summary

The trial evaluates the safety and efficacy of the olfactory mucosa-derived mesenchymal stem cells based therapy for the patients with chronic laryngeal and tracheal stenosis

Clinical Trial Description

Trial evaluating the safety and efficacy of olfactory mucosa-derived mesenchymal stem cells based therapy for the patients with chronic laryngeal and tracheal stenosis with/without cartilage defects Mesenchymal stem cells are obtained from tissue biopsy of olfactory mucosa using explant method. Biomass of autologous mesenchymal stem cells in 10% human albumin solution is injected submucosally around and over the tissue after removal of a granuloma tissue during surgical intervention. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05535803
Study type	Interventional
Source	Institute of Biophysics and Cell Engineering of National Academy of Sciences of Belarus
Contact
Status	Enrolling by invitation
Phase	Phase 2
Start date	June 1, 2021
Completion date	June 30, 2023

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See also
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