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Toxemia clinical trials

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NCT ID: NCT02959229 Completed - Neonatal Sepsis Clinical Trials

Early Versus Late Lactoferrin in Prevention of Neonatal Sepsis

Start date: August 2014
Phase: Phase 4
Study type: Interventional

The present study was designed to evaluate the effectiveness of oral lactoferrin in prevention of neonatal sepsis with comparison early (1st day) versus late (48-72 hours) Lactoferrin administration, Secondary aim was to study effect of Lactoferrin administration on serum Ferritin and follow up long term outcome (Bronchopulmonary dysplasia, retinopathy of prematurity and necrotizing enterocolitis.

NCT ID: NCT02954926 Completed - Neonatal Sepsis Clinical Trials

Intravenous Immunoglobulin in Prevention of Preterm Neonatal Sepsis

Start date: November 2015
Phase: Phase 3
Study type: Interventional

Majority of healthcare authorities believe that due to the methodological weakness and small number of patients in conducted therapeutic trials, the evidences are insufficient to support the efficacy of intravenous immunoglobulin (IVIG) in prevention of preterm neonatal sepsis. The objective of this research is to determine the effect of intravenous immunoglobulin in prevention of preterm neonatal sepsis.

NCT ID: NCT02953002 Completed - Sepsis Clinical Trials

The Correlation Between The New Sepsis Scores - SOFA, Quick SOFA and Calibrated Automated Thrombogram Values

Start date: January 17, 2017
Phase:
Study type: Observational

In total 200 subjects with diagnosis of sepsis, are planned for inclusion in this trial. After signing an informed consent a blood sample will be obtained from each participant. The investigators will measure the thrombin generation in plasma assessed by the calibrated automated thrombogram (CAT). Sequential Organ Failure Assessment score SOFA will be calculated. The relation between SOFA score and thrombin measurements will be determined.

NCT ID: NCT02934997 Completed - Sepsis Clinical Trials

The Role of Dysfunctional HDL in Sepsis

Start date: November 1, 2016
Phase:
Study type: Observational

To determine the role of dysfunctional high density lipoprotein (Dys-HDL) in predicting or mediating progression to chronic critical illness or morbid long-term outcomes in patients being treated for community-acquired or hospital-acquired sepsis.

NCT ID: NCT02927054 Completed - Sepsis Clinical Trials

Effect of Education on Resident Physician Knowledge of Sepsis

Start date: July 2014
Phase: N/A
Study type: Interventional

A questionnaire was provided, including clinical vignettes and free text answers, to assess and evaluate the ability of resident physicians to identify systemic inflammatory response syndrome (SIRS), sepsis, and severe sepsis. Questionnaire scores were compared between specialties. A whole-hospital educational campaign was provided with the aim to improve sepsis recognition, and the questionnaire survey was repeated after one year to assess the effect of the education on the recognition of sepsis.

NCT ID: NCT02898961 Completed - Sepsis Clinical Trials

Impact of 30 mg/kg Amikacin and 8 mg/kg Gentamicin on Serum Concentrations in Critically Ill Patients With Severe Sepsis

Aminoside_II
Start date: October 2014
Phase: Phase 4
Study type: Interventional

Low first-dose peak serum concentrations of amikacin and gentamicin are commonly reported in ICU patients. The present study aimed to assess whether 30 mg/kg amikacin or 8 mg/kg gentamicin achieved target concentrations in ICU patients with severe sepsis.

NCT ID: NCT02891174 Completed - Pre-eclampsia Clinical Trials

The Effect of Ibuprofen on Post-partum Blood Pressure in Women With Hypertensive Disorders of Pregnancy

Start date: December 1, 2016
Phase: Phase 4
Study type: Interventional

To assess the effect of routine doses of ibuprofen on post-partum blood pressure control in women with gestational hypertension (gHTN) or preeclampsia without severe features (preE).

NCT ID: NCT02883595 Completed - Sepsis Clinical Trials

Efficacy of Thymosin Alpha 1 on Improving Monocyte Function for Sepsis

Start date: March 31, 2016
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine whether thymosin alpha 1 is effective on improving monocyte function and has the desired pharmacologic activity for sepsis

NCT ID: NCT02883218 Completed - Sepsis Clinical Trials

Dynamic Alterations of Th2/Th1 With New Onset of Community-acquired Severe Sepsis Patients

Start date: September 2014
Phase:
Study type: Observational

To evaluate the dynamic alterations of Th2/Th1 for the prediction of clinical immunity and how it was related to 28 day-prognosis and ICU-acquired infections among critically ill patients of community-acquired severe sepsis with new onset.

NCT ID: NCT02871544 Completed - Sepsis Clinical Trials

Predictive Value of Dynamic Combination of BNP and NGAL for the Prognosis of Patients With Sepsis

Start date: June 2015
Phase: N/A
Study type: Interventional

Objective: to clarify the predictive value of brain natriuretic peptide (BNP) in combination with neutrophil gelatinase associated lipocalin (NGAL) for the prognosis of patients with sepsis.