Tic Disorders Clinical Trial
Official title:
Open Label Trial of Aripiprazole in Children and Adolescents With Tourette's Disorder
The purpose of this study is to determine if Abilify will reduce tics (repetitive, uncontrollable movements or vocalizations) in children and adolescents ages 7-18 with Tourette's Disorder (TD) or a chronic motor tic disorder (either repetitive, uncontrollable movements or vocalizations).
The aims of this study are to obtain systematic data regarding dosing and safety of aripiprazole (Abilify) in the treatment of youth with Tourette's Disorder (TD). Tourette's Disorder is characterized by multiple motor (more than one uncontrollable movement) and vocal tics (vocal outbursts) which have been present for more than 1 year, with onset before the age of 18. The disorder causes marked distress in social, occupational or other important areas of functioning. Abilify has been approved by the United States Food and Drug Administration (FDA) to treat adults with schizophrenia but has not been approved to treat Tourette's Disorder (TD) so it is considered experimental or investigational in this study. ;
Allocation: Non-Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT05370391 -
Comprehensive Behavioral Intervention for Tics
|
N/A | |
| Completed |
NCT04007913 -
Incorporating teleCBIT Into a Hospital-Based Tic Program
|
N/A | |
| Completed |
NCT04498364 -
Extinction Learning in Adults With Tourette Syndrome
|
N/A | |
| Recruiting |
NCT03844919 -
TICS: Transcranial Magnetic Stimulation for Intervening in Children With Tourette's Syndrome (CIHR)
|
N/A | |
| Not yet recruiting |
NCT06081348 -
Sertraline vs. Placebo in the Treatment of Anxiety in Children and AdoLescents With NeurodevelopMental Disorders
|
Phase 2 | |
| Completed |
NCT00231985 -
Effectiveness of Behavior Therapy and Psychosocial Therapy for the Treatment of Tourette Syndrome and Chronic Tic Disorder
|
Phase 2 | |
| Recruiting |
NCT06050369 -
Objective Characterizatoion of Repetitive Behaviors
|
N/A | |
| Completed |
NCT04578912 -
Transcranial Magnetic Stimulation to Augment Behavior Therapy for Tics
|
N/A | |
| Completed |
NCT03483493 -
Online Remote Behavioural Intervention for Tics (ORBIT)
|
N/A | |
| Recruiting |
NCT06408662 -
Remote Delivery of a Mindfulness-based Intervention for Tics
|
N/A | |
| Withdrawn |
NCT04765085 -
Clinical Efficacy and Change of Life Quality Through Using the Comprehensive Behavioral Intervention Treatment for Tics
|
N/A | |
| Completed |
NCT02676492 -
A Naturalistic Study Investigating Sleep and Cognitive Learning in Children With and Without Tic Disorders
|
N/A | |
| Recruiting |
NCT01860300 -
Efficacy of Amoxicilline/Clavulanic Acid in Patients Affected by Tic Disorder Colonized by Group A Streptococcus
|
N/A | |
| Completed |
NCT00001667 -
Genotype/Phenotype Correlation of Movement Disorders and Other Neurological Diseases
|
N/A | |
| Completed |
NCT00056420 -
Brain Dynamics Involved in Generating Tics and Controlling Voluntary Movement
|
N/A | |
| Completed |
NCT04128397 -
An Exploratory Study of Continuous Theta Burst Stimulation (cTBS) Based on fMRI in the Treatment of Tic Disorder
|
N/A | |
| Recruiting |
NCT05547854 -
Evaluation of an Online Comprehensive Behavioral Intervention for Tics (CBIT) Therapist Training Program
|
N/A | |
| Completed |
NCT05047705 -
Investigating Distress Tolerance in Adults With Tourette Syndrome
|
N/A | |
| Completed |
NCT03564132 -
Evaluating the Efficacy and Safety of Yi-Gan San in Children and Adolescents With Tourette's Disorder
|
Phase 2 | |
| Completed |
NCT03239210 -
Effects of Ondansetron in Obsessive-compulsive and Tic Disorders
|
Phase 4 |