ChloraPrep Versus Betadine for Elective Knee Replacement Surgery

Status Terminated

Clinical Trial Summary

This study will enroll patients who will be receiving primary total knee replacements. Subjects will be randomized into two groups: Betadine surgical scrub preparation and ChloraPrep preparation prior to total knee replacements.

Study hypothesis: When used as a surgical scrub preparation prior to primary total knee arthroplasties, ChloraPrep (2% chlorhexadine gluconate and 70% isopropyl alcohol) is superior to Betadine (10% povidone iodine) in reducing incision site bacterial colony counts.

Clinical Trial Description

Swabs will be taken over the operative knee by study personnel for a bacterial colony count immediately before surgical site preparation is started, after the surgery prep is complete, and 24 hours post surgery prep. Swabs will be sent to the lab for quantitative colony counts and all 3 measurements will be compared and analyzed. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT01184196
Study type	Interventional
Source	Central DuPage Hospital
Contact
Status	Terminated
Phase	Phase 4
Start date	November 2009
Completion date	December 2012

View Details

See also
Status	Clinical Trial	Phase
Terminated	`NCT04040985` - Legion Primary Safety and Efficacy	N/A
Recruiting	`NCT05279092` - Yale Steroid Enhanced Versus Exparel Nerveblock TKA RCT Study	Phase 2
Completed	`NCT03286543` - Electrical Stimulation for the Treatment of Pain Following Total Knee Arthroplasty Using the SPRINT Beta System	N/A
Not yet recruiting	`NCT04594447` - Physica System KR vs Physica System CR (K-20)	N/A
Completed	`NCT02413996` - Effects of Virtual Reality Rehabilitation in Patients With Total Knee Arthroplasty	N/A
Completed	`NCT01500252` - Patellar Resurfacing Versus Patellar Retention in Total Knee Arthroplasty - A Randomized Clinical Trial	Phase 4
Recruiting	`NCT04081493` - The Efficacy of Low-load Blood Flow Restricted Resistance Before TKR	N/A
Active, not recruiting	`NCT03339557` - Comparison of Three Knee Replacements	N/A
Enrolling by invitation	`NCT04513145` - Adductor Canal Block	Phase 2/Phase 3
Completed	`NCT06045078` - Aromatherapy in Total Knee Replacement	N/A
Completed	`NCT02468934` - Electrical Stimulation for the Treatment of Pain Following Total Knee Arthroplasty (TKA) Using the SPRINT System	N/A
Completed	`NCT02914210` - Virtual vs. Traditional Physical Therapy Following Total Knee Replacement	N/A
Withdrawn	`NCT01523418` - Study to Observe Safety of Xarelto in VTE Prophlylaxis After Elective TKR (Total Knee Replacement) or THR (Total Hip Replacement)	N/A
Completed	`NCT00795223` - Comparative Pain Control Between 0.2 or 0.3 Spinal Morphine and 0.25 or 0.5 % Bupivacaine for FNB After TKA	Phase 4
Completed	`NCT01307202` - Morphine Consumption in Joint Replacement Patients, With or Without Gabapentin Treatment	N/A
Completed	`NCT01515449` - Predictors of Poor Outcomes in 1038 Sigma Knees	N/A
Completed	`NCT01522781` - 10 Year Outcome of Total Knee Replacement (TKR) Using Sigma Prosthesis	N/A
Completed	`NCT04166539` - Neurotoxicity and Cardiotoxicity in Total Joint Arthroplasty
Completed	`NCT03454256` - Virtual Reality Rehabilitation in Patients With Total Knee Replacement	N/A
Enrolling by invitation	`NCT06118073` - Effect of Mindfulness on Pain After Total Knee Arthroplasty	N/A