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Clinical Trial Summary

The purpose of this clinical study was to compare the effectiveness of passive ultrasonic irrigation with that of traditional syringe irrigation on the removal of bacteria and endotoxin (lipopolysaccharide [LPS]) from root canals.


Clinical Trial Description

Forty teeth with apical periodontitis were randomly allocated into two groups according to the irrigation protocol, passive ultrasonic irrigation (PUI, n = 20) and syringe and needle irrigation (NI, n = 20). Microbiological sampling was performed before (S1) and after the root canal preparation (S2), after the tested irrigation protocols (S3). Total bacteria counts were determined by a quantitative PCR (qPCR) assay; and the endotoxin levels by the LAL assay. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT02917642
Study type Interventional
Source University of Sao Paulo
Contact
Status Completed
Phase N/A
Start date January 2014
Completion date December 2016

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