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Tooth, Nonvital clinical trials

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NCT ID: NCT05256667 Recruiting - Tooth, Nonvital Clinical Trials

Comparison Between RCT in Single and Two Visits, With and Without Intracanal Dressing, in Apical Repair

Start date: October 2, 2021
Phase: Phase 2/Phase 3
Study type: Interventional

This is a randomized, prospective, double-blind, controlled clinical trial designed to evaluate 3 distinct clinical approaches used during endodontic therapy: Group 1- Root canal treatment in single visit (RCT-SV); Group 2- Root canal treatment in two visits with intracanal dressing (RCT-TVWD); Group 3- Root canal treatment in two visits without intracanal dressing (RCT-TVWOD). A total of 210 adult patients ages 18 to 60 years, with at least one tooth diagnosed with asymptomatic apical periodontitis and periradicular lesion will be randomized and will undergo one of the types of clinical approaches during endodontic therapy. Patients' postoperative pain levels will also be recorded in periods of 24, 48, 72 hours and 7 days. Subsequently, clinical findings and long-term follow-up evaluations, with periradicular repair will be performed by periapical radiograph and computed tomography (cone-beam) at 6th, 12th and 24th months.

NCT ID: NCT05084742 Recruiting - Clinical trials for Endodontically Treated Teeth

Long-term Performance and Safety of Biodentine™ in Patients Treated for Endodontic Indications

Start date: November 8, 2021
Phase:
Study type: Observational

In this observational, retro-prospective, and multicenter PMCF clinical investigation, Biodentine™, an active dentine substitute for professional dental use only, is evaluated at 10 years post-treatment, in its endodontic indications as followed: - Repair of root or furcation perforations. - Repair of root resorptions (internal and external). - Root-end filling in endodontic surgery (retrograde filling). - Apexification (tooth with open apex). - Revitalization procedure by means of revascularization. Evaluation is done through a 10-year post-treatment follow-up with collection of radiographic, clinical examination and safety data.

NCT ID: NCT04838483 Recruiting - Dental Caries Clinical Trials

Clinical Performance of Posterior Indirect Adhesive Restorations

Start date: March 1, 2021
Phase: N/A
Study type: Interventional

Clinical performance of indirect adhesive restorations - onlays, overlays- luted with light-cured composite resin will be evaluated.

NCT ID: NCT04817579 Recruiting - Clinical trials for Discoloration, Tooth

Dental Photography and Numeric Shade Quantification as a Substitute to Conventional and Instrumental Shade Matching Techniques in the Esthetic Zone

Start date: August 2022
Phase: N/A
Study type: Interventional

Visual shade matching is the most common method, in which a color standard from a commercially available dental shade guide is compared to and matched with the target tooth. However, several factors can contribute to perception errors including: different lighting variables, multiple shade systems available in the market with lack of standardization in color systems and corresponding porcelain systems, individual human variables in color perception and lack of understanding of color science. Therefore, in order to eliminate the uncontrolled variables during the color matching process, instrumental methods have been developed. Spectrophotometric measurement methods employing computer calculations, based on color science and theories, allow quantitative evaluation which is objective and appears to be more accurate. However, extremely high costs, relatively low performance with respect to agreements of the computer-aided devices, and edge loss error make it less acceptable. One of the most powerful tools in communicating with both patients and dental ceramists is digital photography. Hence, this study is designed to explore the possibilities of a novel approach to shade management (eLABor_aid) utilizing a photocolorimetric (PCM) method and subsequent shade formulation without the use of stock shade guides in comparison to well-known visual and instrumental methods. The aim of the study is to evaluate the accuracy of digital photography combined with shade analyzing software (eLAB) in optimizing shade matching when compared to conventional and instrumental methods of shade selection. A Null Hypothesis is suggested where no significant difference regarding shade selection between eLAB protocol, conventional and instrumental methods will be found.

NCT ID: NCT04805281 Recruiting - Clinical trials for Endodontically Treated Teeth

Wear Behavior of Milled Posterior Crowns Fabricated From the New Monolithic Zirconia 5Y-TZP/3Y-TZP Compared to Lithium Disilicate

Start date: August 1, 2021
Phase: N/A
Study type: Interventional

In-vitro studies do not represent the actual masticatory environment and cannot simulate the intricate chewing pattern. Hence, there is a need for an in vivo study evaluating the wear potential of the newly introduced strength - color gradient multilayered zirconia IPS e.max ZirCAD Prime (5Y-TZP/3Y-TZP) and compare it to Lithium Disilicate IPS e.max CAD which has proven to have favorable wear patterns.

NCT ID: NCT04738513 Recruiting - Clinical trials for Endodontically Treated Teeth

One Year Clinical Evaluation of New Gradient Technology Monolithic Zirconia (5Y-TZP/3Y-TZP) Crowns in Dental Esthetic Zone With Vertical Versus Conventional Preparation Techniques

Start date: March 1, 2021
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate the clinical behavior of zirconia crowns in dental esthetic zone with vertical versus conventional preparation techniques using a new gradient technology monolithic zirconia (5Y-TZP/3Y-TZP).

NCT ID: NCT04528979 Recruiting - Clinical trials for Endodontically Treated Teeth

Outcome of Endodontic Treatment and Retreatment With a Bioceramic Sealer

Start date: September 20, 2019
Phase: N/A
Study type: Interventional

This study is a prospective randomized controlled study of patients who come to the University. The aim is to evaluate the success rate of treatment and retreatment of canals using BioRoot ™ RCS cement compared with AH Plus up to 6 years of follow-up. The null hypothesis is that there will be no statistically significant differences in rates of successful treatment of root canals filled with BioRoot ™ RCS compared to gutta-percha and AH Plus sealer.

NCT ID: NCT04527705 Recruiting - Clinical trials for Endodontically Treated Teeth

Outcome of Endodontic Retreatment in One or Two Visits

Start date: September 20, 2018
Phase: N/A
Study type: Interventional

This study is a prospective randomized controlled study of patients who come to the University and non-surgical root canal retreatment is considered as the election of choice in presence of periapical disease. The aim is to evaluate the success rate of non-surgical retreatment performed in one compared to two visit treatment up to 10 years of follow-up. The null hypothesis is that there will be no statistically significant differences in rates of success, when performing root canal non-surgical retreatment in one or two visits.

NCT ID: NCT04293770 Recruiting - Dental Caries Clinical Trials

Clinical Evaluation of Posterior Indirect Adhesive Restorations

Start date: December 10, 2019
Phase: N/A
Study type: Interventional

Clinical performance of indirect adhesive restorations - onlays, overlays- luted with light-cured composite resin will be evaluated over three years.

NCT ID: NCT04258696 Recruiting - Clinical trials for Endodontically-Treated Teeth

Assessment of Lateral and Vertical Tissue Displacement Obtained by the Retraction Cord and Diode Laser

Start date: June 30, 2020
Phase: N/A
Study type: Interventional

In fixed prosthodontic treatment, deflection of gingival tissues for diagnosis or making an impression is one of the important phases. Gingival displacement is defined as "displacement of gingival tissues both in vertical and lateral dimensions". Lateral retraction displaces the tissues so that an adequate bulk of impression material can be interfaced with the prepared tooth. Vertical retraction exposes the uncut portion of the tooth apical to the finish line Conventional gingival retraction cord technique may injure the healthy epithelial lining and result in postoperative gingival recession The diode laser has been used for displacing gingiva to make a definitive impression. Rather than displacing gingival tissue, it removes the epithelial lining from the sulcus. The aim of the Study is to compare between the Ultrapak retraction cord and diode laser regarding the amount of vertical and lateral retraction and patient comfort.