OC and ICTP in Gingival Crevicular Fluid During Piezocision Accelerated Orthodontic Treatment

Tooth Movement Clinical Trial

Official title:
Osteocalcin and Cross-Linked C-Terminal Telopeptides of Type I Collagen in Gingival Crevicular Fluid During Piezocision Accelerated Orthodontic Tooth Movement

Status Completed

Clinical Trial Summary

The aim of this study was to evaluate the tooth movement with and without piezocision with regard to the levels of osteocalcin and cross-linked C-terminal telopeptides of type I collagen in the gingival crevicular fluid.

Clinical Trial Description

15 systemically healthy subjects requiring extraction of the maxillary 1. premolars with distalization of the maxillary canines were enrolled to the study. Piezocisions were performed on the distal and mesial sides of the right maxillary canines while the left maxillary canines served as controls. Canine distalization was performed via closed-coil springs applying 150 g of force per side by using miniscrews as anchorage. Gingival crevicular fluid samples were collected from both mesial and distal sides of right and left maxillary canines at 0, 1, 7, 14 and 28 days. The gingival crevicular fluid levels of osteocalcin and cross-linked C-terminal telopeptides of type I collagen were determined by using ELISA. The rate of tooth movement was measured on 14 and 28 days. ;

Study Design

Related Conditions & MeSH terms

Tooth Movement

Clinical Trial Details

NCT number	NCT04611984
Study type	Interventional
Source	Marmara University
Contact
Status	Completed
Phase	N/A
Start date	March 2013
Completion date	August 2014

View Details

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