Impact of Tooth Loss and Denture on Oral Senses and Food Preferences

Tooth-loss Clinical Trial

— AlimaPAC  

Official title:

Impact of Complete Tooth Loss and Denture on Oral Sensory Abilities and Food Preference

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT04281056
• Other study ID #: APHP190340
• Status: Not yet recruiting
• Phase: N/A
• Start date: July 2020
• Est. completion date: July 2020

Study information

• Verified date: February 2020
• Source: Assistance Publique - Hôpitaux de Paris
• Contact: Adeline Braud, Doctor
• Phone: 01 40 19 39 87
• Email: adeline.braud[@]aphp.fr
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Tooth loss impacts taste abilities and food intake. Present study aims at pertaining the impact of teeth loss and the replacement by means of complete denture on taste and trigeminal abilities, and on food preferences, and taste appetence.

Description:

Two groups of participants will be included. Participants wearing complete denture for at least one year (n=20) and their matched controls for age, sex, tobacco, and saliva secretion (n=20). Their oral sensory abilities of participants will be assessed including taste (electrogustometric thresholds, chemical taste identification ability) and trigeminal quantitative sensory testing. Food preferences and selectivity (Maitre et al., 2014) and taste appetence (Deglaire et al., 2012) will also be assessed.

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 40
• Est. completion date: July 2020
• Est. primary completion date: July 2020
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 79 Years

Eligibility

Inclusion Criteria:

Study Group : being completely edentulous and wearing denture for at least one year, wearing denture during meals, with clean and stable dentures. Controls:

controls Group : dentate subjects (25 teeth at leas, non endodontically treated) with molars in Angle's Class I occlusion, having no functional disturbance of mastication and not undergoing dental treatment at the time of the recording. Matched with subjects of the study group for age, sex, tabacco consumption, and saliva flow rate.

Exclusion Criteria:

• Aged under 18 or over 80 Y,

• not consenting to participate

• suffering from dental

• periodontal or gum pain for the last month.

Related Conditions & MeSH terms

• Tooth Loss
• Tooth-loss

Intervention

Procedure:
• Tooth removal and their replacement by means of a denture
Teeth have been removed and replaced by means of dentures for at least one year

Locations

Country	Name	City	State
France	Service odontologie Hôpital Rothschild	Paris

Sponsors (1)

Lead Sponsor	Collaborator
Assistance Publique - Hôpitaux de Paris

Country where clinical trial is conducted

France, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	taste detection thresholds	Using an Electrogustometer	up to 30 days
Secondary	Chemical taste identification ability	Using taste strips (Burghard)	up to 30 days
Secondary	Quantitative sensory testing	Using an algometer, von frey filament, a thermode.	up to 30 days
Secondary	Food preferences and selectivity	Questionnaire food selectyivity and preference (Maitre et al., 2014)	up to 30 days
Secondary	Taste appetence	Questionnaire PrefQuest (Deglaire et al., 2012)	up to 30 days