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Ketamine on Acute Pain in Females and Males

Tooth, Impacted Clinical Trial

Official title:
Effect of Racemic Ketamine on Pain in Females and Males After Surgical Removal of Third Molars

Clinical Trial Summary

The purpose of the study is to determine whether equal subanesthetic doses of racemic ketamine is equally effective on females and males after surgical removal of third molars

Clinical Trial Description

Ketamine is assumed to be a NMDA receptor antagonist which provides analgesia from acute postoperative pain(and other types of pain) subanesthetic doses. Gender differences in ketamine analgesia are not known. This placebo-controlled,randomised, parallel group study investigates the analgesic dose-response effect of ketamine in subanesthetic doses in female and male patients following surgical removal of third molars.

Comparisons: Placebo and ketamine in females and males. ;

Study Design

Allocation: Randomized, Endpoint Classification: Pharmacodynamics Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00232492
Study type Interventional
Source Oslo University Hospital
Contact
Status Completed
Phase Phase 4
Start date January 2005
Completion date November 2006
View Details
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