Tooth Hypersensitivity Clinical Trial
Official title:
Effectiveness of Bioactive Resin Based Varnish and Fluoride Varnish Containing Xylitol-coated Particles Versus Sodium Fluoride Varnish in Management of Teeth Hypersensitivity in Adult Patients Over Eight Weeks: A Randomized Clinical Trial.
Will the use of Bio-smart Light Cured Protective Shield with bioactive S-PRG filler or the use of Sodium Fluoride with Xylitol-coated Calcium and Phosphate (CXP™) Varnish be able to reduce the teeth hypersensitivity similar to Sodium Fluoride Varnish?
The null hypothesis tested in this study, that there is no difference in clinical
effectiveness between bio-smart Shield with bioactive S-PRG filler and Fluoride varnish
containing Xylitol-coated Calcium and Phosphate (CXP™) Compared to Sodium Fluoride Varnish in
management of hypersensitivity in adult patients after 1, 4 and 8 weeks.
P (Population): Patient with Teeth Hypersensitivity.
Intervention-1: Bio-smart Light Cured Protective Shield with bioactive S-PRG (Surface
Pre-Reacted Glass ionomer) filler technology (PRG Barrier Coat) by (By SHOFU Inc., Japan).
Intervention-2: 5% Sodium Fluoride with Xylitol-coated Calcium and Phosphate (CXP™) Varnish
(Embrace™ Varnish) by (Pulpdent Corporation)
C (Comparator): 5% Sodium Fluoride Varnish (Duraphat®) by (Colgate Palmolive Company, New
York, NY)
O (Outcome):
- Primary Outcome: Pain due to Hypersensitivity
- Secondary Outcome: Mineral Content
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