Tooth Erosion Clinical Trial
— UMETOfficial title:
Preliminary Clinical Study of Ultrasound to Measure Enamel Thickness
The investigators have now established a technique to measure enamel thickness which has been shown to work well in-vitro. The teeth tested so far, obtained from the Dental School Tissue Bank, have been molars or pre-molars. In these cases, the measurement is made more difficult by the curvature of the tooth surface and it seems likely that flatter larger, incisors would give more satisfactory results. The investigators therefore wish to establish in-vivo whether this hypothesis is correct.
Status | Completed |
Enrollment | 30 |
Est. completion date | December 2012 |
Est. primary completion date | December 2012 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | Both |
Age group | 18 Years and older |
Eligibility |
Inclusion Criteria: 1. Healthy adults over 18 years (females and males) with normal salivary flow. 2. Volunteers with absence of dental caries and/or periodontal disease on the maxillary incisors (upper front teeth) to be used in the study. 3. Volunteers should have sound maxillary incisors with no obvious cracks in the crown. 4. Volunteers who willingly signed an informed consent. 5. Volunteers who are willing to follow the research schedule for the period of the study. Exclusion Criteria: 1. Volunteers with abnormal enamel on maxillary incisors assessed by visual inspection. 2. Volunteers with replaced enamel on maxillary incisors (eg fillings, crowns, bridges). 3. Volunteers who appear to have hypoplastic teeth as part of a syndrome, e.g. osteogenesis imperfect. 4. Volunteers having orthodontic appliances on front teeth, or presence of fixed or removable dentures (replacing missing front teeth). 5. Volunteers who have a complex dental history such as periodontitis, dentine sensitivity or salivary dysfunction. 6. Volunteers who have any condition could be expected to interfere with the volunteer's safety during the study. 7. Volunteers who demonstrate an inability to comply with study procedures. 8. Signed informed consent not obtained by the volunteer. |
Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Diagnostic
Country | Name | City | State |
---|---|---|---|
United Kingdom | University of Leeds, Leeds Dental Institute (DenTCRU) | Leeds | West Yorkshire |
Lead Sponsor | Collaborator |
---|---|
University of Leeds |
United Kingdom,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Enamel thickness reproducibility measurements | To know if ultrasound can reliably and reproducibly measure enamel thickness in-vivo | 2 weeks | No |
Secondary | Enamel thickness reproducibility measurements on separate occasions | To investigate whether ultrasound can be used to reproducibly measure enamel thickness on human incisor teeth in vivo on three separate occasions | 2 weeks (concurrent with primary outcome) | No |
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