Tonsillitis Clinical Trial
Official title:
A Randomized, Single-blind, Prospective Trial of Auricular Acupuncture for the Reduction of Post-operative Tonsillectomy Pain in Adults
The purpose of this study is to determine if auricular acupuncture significantly reduces post-operative pain in comparison to the standard of care. Post-operative pain score will be collected by subject self-report of pain according to the Numerical Rating Scale (NRS) (0= no pain, 10 = worst imaginable pain) up to 10 days post-operation.
DESIGN:
Design type: Prospective, randomized control trial Sample
- Description of the population: All adults, greater than or equal to 18 years, undergoing
a tonsillectomy with or without adenoidectomy at Womack Army Medical Center are eligible
for participation in the study.
- Sample Size: 100 subjects. A target of 45 subjects per group for a total of 90 subjects,
and accounting for a 10 percent drop out rate. In Fiscal Year 12, 92 tonsilectomies in
patients over the age of 12 were performed at Womack Army Medical Center. Therefore, the
investigators anticipate the study will take up to 4 years to enroll 100 adult subjects.
- Power Analysis: Under the assumption of a linear time by treatment interaction, assuming
subject-level randomization, five time-points, power of 80 percent, a Type I error rate
of 5 per cent and no attrition, to detect a 1.6 difference in pain score requires a
total sample size of 90 subjects or 45 per treatment arm.
;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT04083417 -
Sore Throat in Primary Care - a Comparison of Phenoxymethylpenicillin and no Antibiotic Treatment
|
Phase 4 | |
| Completed |
NCT04551196 -
Management of Post-Tonsillectomy Pain in Pediatric Patients
|
Phase 3 | |
| Active, not recruiting |
NCT03654742 -
Intracapsular Tonsillectomy in Adults
|
N/A | |
| Completed |
NCT04016051 -
Acceptance of Clarithromycin in a Straw Compared to Syrup in Children With Upper Respiratory Tract Infections
|
Phase 3 | |
| Completed |
NCT02712307 -
Study of 5 and 10 Days Treatment With Penicillin Against Sore Throat Caused by Streptococci
|
Phase 4 | |
| Enrolling by invitation |
NCT02205580 -
Continuous Intravenous Sufentanil Infusion for Postoperative Pain Management Following Tonsillectomy or Adeno-tonsillectomy in Children
|
Phase 4 | |
| Completed |
NCT01721486 -
Acetaminophen's Efficacy For Post-operative Pain
|
Phase 4 | |
| Active, not recruiting |
NCT01691690 -
Analgesic Effect of IV Acetaminophen in Tonsillectomies
|
Phase 2 | |
| Completed |
NCT00393744 -
Efficacy Study of Pristinamycin Versus Amoxicillin to Treat Tonsillitis Induced by Streptococcus in Children
|
Phase 3 | |
| Completed |
NCT00095368 -
APC-111 Once a Day (QD) for 7 Days vs. Penicillin Taken Four Times a Day (QID) for 10 Days in Patients With Strep Throat
|
Phase 3 | |
| Active, not recruiting |
NCT00136877 -
Tonsillectomy in Recurrent Tonsillitis
|
N/A | |
| Recruiting |
NCT04646525 -
The Relationship Between Covid-19 Infection in Pediatric Patients and Secondary Lymphoid Organs
|
||
| Completed |
NCT01361399 -
Active and Placebo Controlled Study to Test the Efficacy and Safety of an Aspirin-Lidocaine Lozenge in the Symptomatic Treatment of Sore Throat Associated With a Common Cold
|
Phase 3 | |
| Recruiting |
NCT03137823 -
Diagnosis of GABHS Tonsillitis - Comparison Between Culture From Tonsills and Culture From the Bucal Surface
|
N/A | |
| Completed |
NCT00547391 -
Recurrent Throat Infections and Tonsillectomy
|
Phase 4 | |
| Completed |
NCT00242281 -
APC-111 MP Tablet Once a Day vs.Penicillin VK Four Times a Day Both for 10 Days in Patients With Strep Throat
|
Phase 3 | |
| Completed |
NCT01465009 -
Placebo and Active Controlled Study to Compare the Efficacy of Aspirin and Paracetamol in Treatment of Sore Throat Associated With a Common Cold
|
Phase 4 | |
| Recruiting |
NCT04164511 -
Does Ice Cream Help With Post-tonsillectomy Pain
|
||
| Completed |
NCT04653376 -
Relationship of Endoplasmic Reticulum Stress and Tonsillar Tissue Diseases
|
||
| Recruiting |
NCT06326983 -
Opioid Sparing Anesthesia Care for Pediatric Patients Having Tonsil Surgery
|
N/A |