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Efficacy of Opioid-free Anesthesia in Reducing Postoperative Respiratory Depression in Children Undergoing Tonsillectomy

Anesthesia Clinical Trial

Official title:
Efficacy of Opioid-free Anesthesia in Reducing Postoperative Respiratory Depression in Children Undergoing Tonsillectomy: a Pilot Study

Clinical Trial Summary

The objective of this trial is to determine whether an opioid-free general anesthetic (OFA) technique utilizing ketamine, dexmedetomidine, lidocaine, and gabapentin can help reduce postoperative respiratory depression in the post-anesthesia care unit and ward in children with sleep-disordered breathing undergoing tonsillectomy when compared with traditional opioid-containing techniques. It is expected that this OFA regimen will have a measurable reduction on postoperative respiratory depression in children with sleep-disordered breathing.

Clinical Trial Description

The objective of this trial is to determine whether an opioid-free general anesthetic can help reduce postoperative respiratory depression in the post-anesthesia care unit and ward in children with sleep-disordered breathing undergoing tonsillectomy when compared with traditional opioid-containing techniques. ;

Study Design

Related Conditions & MeSH terms

  • Analgesics
  • Analgesics, Opioid
  • Anesthesia
  • Depression
  • Depressive Disorder
  • Dexmedetomidine
  • Gabapentin
  • General Anesthesia
  • Ketamine
  • Lidocaine
  • Narcotics
  • Obstructive Sleep Apnea of Child
  • Pathologic Processes
  • Physiologic Effects of Drugs
  • Postoperative Complications
  • Pulse Oximetry
  • Respiratory Depression
  • Respiratory Insufficiency
  • Sleep Apnea Syndromes
  • Sleep Apnea, Obstructive
  • Sleep Disordered Breathing
  • Tonsillectomy
Clinical Trial Details
NCT number NCT02987985
Study type Interventional
Source University of Saskatchewan
Contact
Status Completed
Phase Phase 3
Start date October 15, 2017
Completion date December 20, 2020
View Details
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