Tolerance of the Liver Clinical Trial
Official title:
Safety of Intermittent Pringle Maneuver Cumulative Time Exceeding 120 Min in Liver Resection
| Verified date | October 2010 |
| Source | University of Milan |
| Contact | n/a |
| Is FDA regulated | No |
| Health authority | Italy: Ministry of Health |
| Study type | Observational |
Intermittent Pringle's maneuver is widely used to limit blood loss during hepatectomy, without an established time-limit. However, many authors claims its danger for patients' outcome. The investigators check the short term outcome of a consecutive cohort of patients who underwent hepatectomy with intermittent clamping exceeding 120 minutes.
| Status | Completed |
| Enrollment | 189 |
| Est. completion date | October 2010 |
| Est. primary completion date | October 2010 |
| Accepts healthy volunteers | No |
| Gender | Both |
| Age group | 29 Years to 85 Years |
| Eligibility |
Inclusion Criteria: - patients in whom total cumulative clamping time exceeded 60 minutes. Exclusion Criteria: - patients in whom total cumulative clamping time was less than 60 minutes |
Observational Model: Cohort, Time Perspective: Retrospective
| Country | Name | City | State |
|---|---|---|---|
| Italy | IRCCS Istituto Clinico Humanitas | Rozzano | Milan |
| Lead Sponsor | Collaborator |
|---|---|
| University of Milan |
Italy,
Belghiti J, Noun R, Malafosse R, Jagot P, Sauvanet A, Pierangeli F, Marty J, Farges O. Continuous versus intermittent portal triad clamping for liver resection: a controlled study. Ann Surg. 1999 Mar;229(3):369-75. — View Citation
Elias D, Desruennes E, Lasser P. Prolonged intermittent clamping of the portal triad during hepatectomy. Br J Surg. 1991 Jan;78(1):42-4. — View Citation