Tobacco Use Cessation Clinical Trial
Official title:
Feasibility, Adoption and Efficacy of A Virtual Reality Smoking Cessation Program for Patients Undergoing Lung Cancer Screening: A Pilot Trial
Lung cancer is the second most common cancer and the leading cause of cancer related deaths in the United States (US . Tobacco use is the leading cause of lung cancer and tobacco control continues to be the primary method of lung cancer prevention. Smoking cessation interventions (SCIs) are strongly recommended by screening guidelines and have a class A recommendation by the United States Preventive Services Task Force. Currently, a variety of smoking cessation interventions exist, and evidence suggests that pharmacotherapy, such as nicotine replacement therapy, in combination with behavioral interventions is more effective than either intervention alone. Many individuals, however, prefer not to use or are unable to use pharmacotherapy. A variety of behavioral interventions exist to aid in smoking cession. Recently, virtual reality (VR) has emerged as a possible tool to conduct behavior interventions. Previous research has demonstrated that use of VR can improve patient engagement in a variety of chronic disease interventions. Little is known however about the feasibility and adoption of VR in smoking cessation, especially among individuals at high risk for lung cancers. VR based platforms utilize 'cue exposure therapy'. Given that cravings are often triggered by external factors, or cues, cue exposure therapy exposes individuals to repeated drug-related cues and provides them with tools to eliminate cue-induced cravings. Given the inability for all individuals to use pharmacotherapy there remains a critical need to improve adherence to and efficacy of behavioral interventions for smoking cessation. To address this unmet need, the investigators propose, as pilot study, to enroll patients undergoing routine lung cancer screening and who are not interested in or cannot take pharmacologic therapies for smoking cession, to participate in VR based smoking cessation therapy.
The purpose of this study is to assess the adoption rate of VR smoking cessation intervention (MindCotine app) in those who are at risk for lung cancer and are participating in a lung cancer screening program. The investigators will enroll 20 individuals. 10 of whom elect to participate in the VR program and 10 of whom are using standard of care smoking cessation methods. The study duration is 90 days after completion of the MindCotine VR program. The MindCotine program consists of a 8-week training stage, and includes audiovisual content, cognitive behavioral therapy based self-reflective questions, setting a quit date, and notifications. The audio-visual content includes formal mindfulness exercises involving breathing techniques, body awareness, thought recognition, emotions, and smoking impulses. VR therapy exercises include the following topics: The Act of Smoking; RAIN meditation; Stress at work; Bodily sensations; Deep emotions; Nicotine anonymous; Alcohol as a trigger. Each content consists of a 2 minute animated environment to induce meditative states of mind, 6 minutes of exposure with real people, and 2 more minutes of an animated environment to induce a meditative mindset. Participants will be surveyed at baseline, 1 day after the completion of the 8 week VR program and again 90 days after the completion of the VR program. ;
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT02735382 -
EHR-Based and Fax-Based Referral to a Tobacco Quitline: A Comparative Study
|
N/A | |
Completed |
NCT02557919 -
Families Reduce Exposure to Smoke at Home
|
N/A | |
Completed |
NCT01570595 -
Positively Smoke Free on the Web (PSFW) for Smokers Living With HIV
|
Phase 1/Phase 2 | |
Completed |
NCT00786149 -
Improving Varenicline Adherence and Outcomes in Homeless Smokers
|
Phase 3 | |
Completed |
NCT00387946 -
Efficacy and Safety of Dianicline Treatment as an Aid to Smoking Cessation in Cigarette Smokers (AMERIDIAN)
|
Phase 3 | |
Completed |
NCT00218452 -
Smoking Cessation for Young Adults Who Binge Drink - 1
|
Phase 0 | |
Completed |
NCT00124683 -
Treating Nicotine Dependence in Schizophrenic Individuals: Effectiveness of Bupropion - 1
|
Phase 2 | |
Recruiting |
NCT04610931 -
Study of the Effectiveness of a Virtual Reality Treatment in the Management of Smoking Cessation
|
N/A | |
Enrolling by invitation |
NCT06042361 -
Enhancing Equity in Smoke-free Housing
|
N/A | |
Recruiting |
NCT04994444 -
Preloading With Nicotine Replacement Therapy in HIV-positive Smokers to Improve Self-Efficacy and Quit Attempts
|
Phase 2/Phase 3 | |
Recruiting |
NCT04827420 -
Mi QUIT CARE (Mile Square QUIT Community-Access-Referral-Expansion)
|
N/A | |
Completed |
NCT05560243 -
Tobacco Cessation Tailored to Patients Living With HIV (PLWH) in Brazil
|
N/A | |
Completed |
NCT02721082 -
Changing the Default for Tobacco Treatment
|
Phase 4 | |
Completed |
NCT01885221 -
A Multi-Media Approach to Partner Support in Smokeless Tobacco Cessation (UCare-ChewFree)
|
N/A | |
Completed |
NCT03445507 -
Effectiveness of a Chat Bot for Smoking Cessation: a Pragmatic Trial in Primary Care.
|
N/A | |
Completed |
NCT04540081 -
Enhancing Electronic Health Systems to Decrease the Burden of Colon Cancer, Lung Cancer, Obesity, Vaccine-Preventable Illness, and LivER Cancer
|
N/A | |
Completed |
NCT03714191 -
Optimizing the Tobacco Cessation Clinical Decision Support Tool.
|
||
Completed |
NCT03553992 -
An Extended Facebook Intervention for Young Sexual and Gender Minority Smokers
|
N/A | |
Completed |
NCT01699828 -
Exploring Occupancy of Dopamine D3 Receptor by Buspirone in Humans Using PET
|
Phase 1/Phase 2 | |
Completed |
NCT01328431 -
Treating Low-Income Smokers in the Hospital Emergency Department
|
N/A |