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Pharmacokinetics and Pharmacodynamics of Nicotine With Use of Standardized Research Electronic Cigarette (SREC) — SREC22  

Nicotine Dependence Clinical Trial

Official title:
Comparative Pharmacokinetics and Pharmacodynamics of Nicotine With Use of NIDA Standardized Research Electronic Cigarette (SREC) vs Usual Brand E-cigarette

Clinical Trial Summary

This is a crossover study that will examine use behaviors, chemical exposures, and biological effects of Standardized Research Electronic Cigarette (SREC) compared to usual brand e-cigarette use in natural or synthetic nicotine users.

Clinical Trial Description

OBJECTIVES: I. To characterize nicotine delivery, systemic exposure and effects from SREC in comparison with usual to usual nicotine brand use. II. To assess aspects of harm of SREC use compared to usual nicotine brand use. OUTLINE: Eligible participants will be assigned to one of two treatment conditions for the initial assessment which will take place in a hospital setting. The participant will then be assigned to the second condition within 2 weeks after the initial assessment which will also take place in a hospital setting to repeat the same procedures. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05658471
Study type Interventional
Source University of California, San Francisco
Contact Lisa Lawrence
Phone 415-608-4864
Email Lisa.Lawerence@ucsf.edu
Status Recruiting
Phase N/A
Start date February 1, 2023
Completion date January 31, 2025
View Details
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