Reduced Nicotine Content Cigarettes in Smokers of Lower Socioeconomic Status

Tobacco Dependence Clinical Trial

Official title: Reduced Nicotine Content Cigarettes in Smokers of Lower Socioeconomic Status

Status Completed

Clinical Trial Summary

The overall goal of this study is to address the question of whether progressively lowering nicotine content in cigarettes can reduce or eliminate nicotine dependence in smokers of low socioeconomic status

Clinical Trial Description

To address the question of whether progressively lowering nicotine content in cigarettes can reduce or eliminate nicotine dependence in low socioeconomic smokers, we will randomize smokers to either an Reduced Nicotine Content group with a gradual step-wise reduction in nicotine from 11 mg to 0.2 mg per cigarette in five 3-wk stages, or a control group with nicotine content similar to their preferred usual brand of cigarettes.

Overall, we hypothesize that low socioeconomic smokers who switch to progressively lower nicotine cigarettes will initially alter their smoking behavior to compensate for lower nicotine until cigarette nicotine yields become so low that complete compensation becomes too difficult. At that point, smokers will either drop-out or continue to smoke the reduced nicotine content cigarettes but with incomplete compensatory behaviors. ;

Related Conditions & MeSH terms

• Tobacco Dependence
• Tobacco Use Disorder

• NCT number: NCT01928719
• Study type: Interventional
• Source: Milton S. Hershey Medical Center
• Status: Completed
• Phase: N/A
• Start date: September 9, 2015
• Completion date: February 23, 2018