Comparison Between IPRF With Vit. C and IPRF Alone in Management of ID'Pain

TMJ Pain Clinical Trial

Official title:

Comparison Between Injectable Platelet Rich Fibrin With Vitamin C and Injectable Platelet Rich Fibrin Alone in Management of ID'Pain

Clinical Trial Details — Status: Active, not recruiting

Administrative data

• NCT number: NCT06345092
• Other study ID #: Omfs.3-3-3
• Status: Active, not recruiting
• Phase: N/A
• Start date: April 15, 2024
• Est. completion date: August 15, 2024

Study information

• Verified date: May 2024
• Source: Cairo University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Randomized clinical trial between 2groups,the study group to be injected in the TMJ with injectable platelet rich fibrin with vitamin C and the control group to be injected in the TMJ with injectable platelet rich fibrin alone in management of internal Temporomandibular joint derangement

Description:

Randomized clinical trial between 2groups,the study group to be injected in the TMJ with injectable platelet rich fibrin with vitamin C and the control group to be injected in the TMJ with injectable platelet rich fibrin alone in management of internal Temporomandibular joint derangement

Recruitment information / eligibility

• Status: Active, not recruiting
• Enrollment: 40
• Est. completion date: August 15, 2024
• Est. primary completion date: May 15, 2024
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 40 Years

Eligibility

Inclusion Criteria:

Patients with internal TMJ derangement (anterior disc displacement with reduction)

Exclusion Criteria:

Pathological conditions ; trauma TMJ cases or any blood diseases

Related Conditions & MeSH terms

• TMJ Pain

Intervention

Drug:
• Vitamin C
addition of vitamin C to IPRF

Other:
• Injectable platelet rich fibrin
injection of IPRF alone

Locations

Country	Name	City	State
Egypt	Faculty of Dentistry cairo university	Cairo

Sponsors (1)

Lead Sponsor	Collaborator
Cairo University

Country where clinical trial is conducted

Egypt, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Other	maximum mouth opening	measurement of MMO using digital caliper pre and post injections	at 4;8;12;16 weeks
Other	lateral excursion	measurement of lateral excursion using digital caliper pre and post injections	at 4;8;12;16 weeks
Primary	Pain management	Evaluation of pain using VAS pre and post injections	at 4;8;12;16 weeks
Secondary	disc position using MRI	evaluation of disc position pre and post injections	at 4;8;12;16 weeks