Role of Ultrasonography in Assessment of Tempromanbular Joint Disorders

TMJ Disorder Clinical Trial

Official title:

Role Of Ultrasonography Compared To MR Imaging In Assessment Of Tempromandibular Joint Disorders

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT05320770
• Other study ID #: Soh-Med-22-02-05
• Status: Not yet recruiting
• Phase: N/A
• Start date: February 2023
• Est. completion date: April 2023

Study information

• Verified date: January 2023
• Source: Sohag University
• Contact: Aliaa M Awad
• Phone: 01201240011
• Email: aliaa011119[@]med.sohag.edu.eg
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Evaluation of US efficiency in assessment of the tempromandibular joint disorders in comparison with MRI as the gold standard for technique validation and evaluation of efficiency of therapeutic intra articular injection under sonographic guidance .

Description:

Temporomandibular joint disorders is a common condition, Intra-articular causes of TMD include internal joint derangement, osteoarthritis, capsular inflammation, hypermobility and traumatic injury. The most frequent cause of TMJ dysfunction is internal derangement which refers to an alteration in the normal pathways of motion of the TMJ that largely involves the function of the articular disc, therefore, these alterations have been also referred to as disc derangement , signs of which appear in up to 60-70% of the population. The peak incidence is seen in adults aged 20-40 years. Women are at least four times as likely to suffer from the disorder . Magnetic resonance imaging (MRI) has provided a noninvasive accurate method of assessing the TMJ without associated radiation risks ,its ability to directly visualize the disc and accurately determine the position of the disc with respect to the condyle of the mandible and eminence of the temporal bone. The examination, however, takes 20 to 45 minutes on average to perform depending on the scanner and protocol, and patients have difficulty keeping still and having their mouths open for extended periods of time, especially if they are experiencing pain. In addition, the examination is costly and access is still limited in many centers. Many patients also experience claustrophobia and are unable to complete or even undergo the examination . Ultrasound is relatively inexpensive, is readily accessible, and can be performed in most outpatient facilities; studies take only an average of 10 to 15 minutes in total, and it is without any known risks. In addition, US provides the opportunity to converse with patients and identify the exact locations of pain, while the probe can be used as a palpable tool for real-time identification of crepitus, clicking, motion, and snapping sensations. The following US applications were described: Joint effusion, Internal derangement and disc displacement, mainly anterior with and without reduction, Joint function basing on condylar translation range, TMJ dislocation, Guidance in fine-needle aspiration cytology (FNAC), Guidance for TMJ arthrocentesis and Guidance in TMJ injections, e.g., with steroids , Blood .

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 50
• Est. completion date: April 2023
• Est. primary completion date: March 2023
• Accepts healthy volunteers: No
• Gender: All
• Age group: N/A and older

Eligibility

Inclusion Criteria:

• Male and female diagnosed as TMJ disorders (clinically through history of the presentation and physical examination (site, onset, character of pain, radiation, duration and associated symptoms. This pain may refer to the scalp or neck, and is often exacerbated by mastication, yawning or talking for extended periods. Difficulty opening the mouth, clicking, popping or crepitus within the TMJ itself and brief locking of the mandible on jaw opening and closure and Headache, particularly tension type headache).

Exclusion Criteria:

• Uncooperative patients, systemic disease with TMJ involvement as Rheumatoid, psoriatic, and juvenile idiopathic arthritis. Contraindications for MRI : claustrophobia , metallic implants , pacemaker and prosthetic heart valves .Contraindication for intra articular injection : the patients with bleeding disorders , pregnancy , bony pathology of TMJ , allergy to local anesthetic and those on narcotics or anti depressant .

Related Conditions & MeSH terms

• Joint Diseases
• Temporomandibular Joint Disorders
• TMJ Disorder

Intervention

Procedure:
• US guided TMJ intra articular injection
therapeutic TMJ intra articulatr injection of blood under sonography guidance to reduce joint hyper mobility

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Sohag University

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Change of temporomandibular joint imaging by ultrasonography and magnetic resonance imaging .	Imaging of the temporomandibular joint by ultrasonography and imaging by magnetic resonance imaging .	Ultrasonography at baseline visit and MRI one week after baseline visit .
Primary	Change of mobility of the temporomandibular joint before and after ultrasonography guided blood injection .	Measuring the temporomandibular joint mobility in millimeters by ultrasonography before and after sonar guided injection .	Baseline visit and three months after the baseline intervention .