Tissue Pathology Clinical Trial
Ultrasound (US)tissue elastography has recently been found to have a number of clinical
applications in the assessment of soft tissue disease for example, in breast and thyroid
pathology. There are few current studies exploring its use in musculoskeletal pathology,
particularly a new technique called sheer wave ultrasound elastography (SWUE).
Magnetic Resonance (MR) elastography has shown wide reaching applications in orthopaedics,
sports medicine and rheumatology and SWUE may have the potential to also demonstrate
clinical effectiveness in these areas.
Our aim is to explore the effectiveness of this technique in the assessment of
musculoskeletal pathology.
Participants will be recruited through current referral protocols and would undergo an
additional elastographic investigation in addition to their standard US examination. This
investigation will be conducted within the musculoskeletal US department at Chapel Allerton
Hospital by trained musculoskeletal specialists. The study will be conducted over a period
of approximately 24 months with quarterly review during this time.
| Status | Recruiting |
| Enrollment | 500 |
| Est. completion date | |
| Est. primary completion date | December 2016 |
| Accepts healthy volunteers | No |
| Gender | Both |
| Age group | 16 Years and older |
| Eligibility |
Inclusion Criteria: - Have clinical symptoms and signs of soft tissue pathology - Be able to give consent - Be over 16 years of age Exclusion Criteria: - Unable to give consent - 16years of age or less - Multifactorial soft tissue pathology |
Observational Model: Cohort, Time Perspective: Prospective
| Country | Name | City | State |
|---|---|---|---|
| United Kingdom | Leeds Teaching Hospital NHS Trust | Leeds |
| Lead Sponsor | Collaborator |
|---|---|
| The Leeds Teaching Hospitals NHS Trust |
United Kingdom,
| Type | Measure | Description | Time frame | Safety issue |
|---|---|---|---|---|
| Primary | Clinical effectiveness of Sheer wave ultrasound elastography (SWUE) in the assessment of soft tissue pathology | Ability of SWUE to accurately detect soft tissue pathology when compared with standard ultrasound techniques. | Baseline to 24 months | No |