Tissue Adhesions Clinical Trial
Official title:
Sensitivity and Predictive Value of Functional Cine Magnetic Resonance Imaging (MRI) Detecting Intra-abdominal Adhesions
Official title:
Sensitivity and predictive value of functional cine magnetic resonance imaging (MRI)
detecting intra-abdominal adhesions
Background:
Adhesions are a frequent problem in abdominal surgery. The formation of adhesions is part of
a normal wound healing. However in some patients adhesions cause severe complications such as
chronic pain, obstruction and strangulation of the bowel. Adhesions can also obstruct access
to the peritoneal cavity and complicate reoperations. Accurate imaging of adhesions would be
of benefit avoiding adhesion related complications at repeated laparotomy or laparoscopy. At
present no validated diagnostic tool mapping adhesions exists.
Purpose:
To define the sensitivity and specificity of functional cineMRI in detecting and mapping
adhesions in patients undergoing reoperation.
Design:
Prospective multicenter observational trial
Primary outcome:
Sensitivity and specificity of functional MRI detecting adhesions to the abdominal wall
Secondary outcome:
Sensitivity and specificity of functional MRI detecting organ-to-organ adhesions.
Estimated enrollment: 100
Estimated study completion date: dec 2019
Estimated primary completion date: dec 2019
n/a
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