Treatment for Post Acute COVID-19 Syndrome

Status Not yet recruiting

Clinical Trial Summary

Post-acute COVID-19 tinnitus has not been treated successfully. As tinnitus may be related to SARS-CoV-2 neurological manifestations. This study aims to investigate if the dopamine receptor antagonists can be used effectively treat COVID-19 induced tinnitus.

Clinical Trial Description

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative viral pathogen leading to the COVID-19 pandemic. In 2022, after three successive waves of the pandemic, the majority of the human population has been exposed to the SARS-CoV-2 virus. During the two years since the pandemic ensued, multiple reports emerged of patients experiencing COVID-19 emergent symptoms lasting longer than 4 weeks since onset. Up to 15% of patients recovering from COVID-19 experience post-acute COVID-19 induced tinnitus . To-date, post-acute COVID-19 tinnitus has not been treated successfully. As tinnitus may be related to SARS-CoV-2 neurological manifestations. This study aims to investigate if the dopamine receptor antagonist Pimozide can be used effectively treat COVID-19 induced tinnitus. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05507372
Study type	Interventional
Source	Applied Biology, Inc.
Contact	Andy Goren, MD
Phone	6507040850
Email	andyg@appliedbiology.com
Status	Not yet recruiting
Phase	N/A
Start date	October 1, 2022
Completion date	December 1, 2023

View Details

See also
Status	Clinical Trial	Phase
Recruiting	`NCT04987502` - Virtual Reality and Subjective Tinnitus	N/A
Completed	`NCT04281953` - Impact on Quality of Life of Long-term Ototoxicity in Cancer Survivors
Recruiting	`NCT04404439` - Treatment of Tinnitus With Migraine Medications	Phase 4
Completed	`NCT03782220` - Effects of Kinesio Taping in Patients With Somatosensory Tinnitus	N/A
Completed	`NCT05711641` - Action of Intra-auricular Topical Lidocaine on Tinnitus	N/A
Completed	`NCT03711630` - Impact of Meditation on Bothersome Tinnitus	N/A
Completed	`NCT05591144` - Short-term Oral Prednisone for Acute Subjective Tinnitus	N/A
Completed	`NCT04565132` - HD-tDCS as a Treatment for Chronic Tinnitus	N/A
Completed	`NCT02315508` - Evaluating Possible Improvement in Tinnitus Severity After 28 Days Dosing of the Study Drug AUT00063 Compared to Placebo	Phase 2
Active, not recruiting	`NCT03888521` - Evaluating the GN ReSound Relief App Using task-and Rest-based fMRI	N/A
Recruiting	`NCT05198973` - Bumblebee Breath Effect on Tinnitus in Older Patients	N/A
Not yet recruiting	`NCT04623957` - Safety and Efficacy of Acupressure Applied Through ForgTin© in Patients With Tinnitus	N/A
Recruiting	`NCT05964725` - The Study on Effect and Neural Network Mechanism of Transcranial Direct Current Stimulation for Sudden Deafness With Tinnitus	N/A
Not yet recruiting	`NCT05417711` - Efficacy of Transcutaneous Vagus Nerve Stimulation Paired With Tailor-Made Notched Music Therapy Versus Tailor-made Notched Music Training for Chronic Subjective Tinnitus	N/A
Recruiting	`NCT04162405` - Tinnitus in Patients With and Without Sensorineural Hearing Loss
Completed	`NCT03638986` - Comparison of the Two Validated German Versions of the "Tinnitus Functional Index" for Switzerland and for Germany
Completed	`NCT04127708` - Tinnitus and Acupuncture	N/A
Completed	`NCT03716544` - Efficacy of Amplification With Hearing Aids for Tinnitus Relief	N/A
Not yet recruiting	`NCT06433895` - Efficacy of Manual Therapy in the Treatment of Somatic Tinnitus	N/A
Enrolling by invitation	`NCT04382807` - Internet-delivered Group Counseling for Chronic Tinnitus