Tinnitus, Subjective Clinical Trial
Official title:
The Clinical Effects of Modified Tinnitus Relieving Sound Treatment
Objective Tinnitus is one of the most common acoustic disorders by affecting 5-43% people
around the world, and tinnitus is harmful to social and individuals, inducing to annoyance,
irritability, anxiety, depression, insomnia and concentration difficulties. Many efforts have
been made to help tinnitus suffers, however, the curative means are still in absence. This
study aims to introduce a novel sound therapy for tinnitus and to evaluate the efficacy of
modified tinnitus relieving sound treatment in comparison with unmodified music which served
as a control.
Methods and analysis A randomized, triple-blinded, controlled, clinical trial will be carried
out. 68 patients with subjective tinnitus will be recruited and randomized into two groups in
1:1 ratio. The primary outcomes will be Tinnitus Handicapped Inventory (THI), Hospital
Anxiety and Distress Scale (HADS), and visual analogue scale (VAS) for tinnitus; the
secondary outcome measures will be Athens Insomnia Scale (AIS), tinnitus loudness matched by
sensation level (LM, SL), and minimum masking level (MML). Assessment will be performed at
baseline and at 1, 3, 9, and 12 months post-randomization. The sound stimulus will be
persistent until 9 months after randomization, and be interdictory in the last three months.
n/a
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT04987502 -
Virtual Reality and Subjective Tinnitus
|
N/A | |
| Completed |
NCT04281953 -
Impact on Quality of Life of Long-term Ototoxicity in Cancer Survivors
|
||
| Recruiting |
NCT04404439 -
Treatment of Tinnitus With Migraine Medications
|
Phase 4 | |
| Completed |
NCT03782220 -
Effects of Kinesio Taping in Patients With Somatosensory Tinnitus
|
N/A | |
| Completed |
NCT05711641 -
Action of Intra-auricular Topical Lidocaine on Tinnitus
|
N/A | |
| Completed |
NCT03711630 -
Impact of Meditation on Bothersome Tinnitus
|
N/A | |
| Completed |
NCT05591144 -
Short-term Oral Prednisone for Acute Subjective Tinnitus
|
N/A | |
| Completed |
NCT04565132 -
HD-tDCS as a Treatment for Chronic Tinnitus
|
N/A | |
| Completed |
NCT02315508 -
Evaluating Possible Improvement in Tinnitus Severity After 28 Days Dosing of the Study Drug AUT00063 Compared to Placebo
|
Phase 2 | |
| Active, not recruiting |
NCT03888521 -
Evaluating the GN ReSound Relief App Using task-and Rest-based fMRI
|
N/A | |
| Not yet recruiting |
NCT05507372 -
Treatment for Post Acute COVID-19 Syndrome
|
N/A | |
| Recruiting |
NCT05198973 -
Bumblebee Breath Effect on Tinnitus in Older Patients
|
N/A | |
| Not yet recruiting |
NCT04623957 -
Safety and Efficacy of Acupressure Applied Through ForgTin© in Patients With Tinnitus
|
N/A | |
| Recruiting |
NCT05964725 -
The Study on Effect and Neural Network Mechanism of Transcranial Direct Current Stimulation for Sudden Deafness With Tinnitus
|
N/A | |
| Not yet recruiting |
NCT05417711 -
Efficacy of Transcutaneous Vagus Nerve Stimulation Paired With Tailor-Made Notched Music Therapy Versus Tailor-made Notched Music Training for Chronic Subjective Tinnitus
|
N/A | |
| Recruiting |
NCT04162405 -
Tinnitus in Patients With and Without Sensorineural Hearing Loss
|
||
| Completed |
NCT04127708 -
Tinnitus and Acupuncture
|
N/A | |
| Completed |
NCT03638986 -
Comparison of the Two Validated German Versions of the "Tinnitus Functional Index" for Switzerland and for Germany
|
||
| Completed |
NCT03716544 -
Efficacy of Amplification With Hearing Aids for Tinnitus Relief
|
N/A | |
| Not yet recruiting |
NCT06433895 -
Efficacy of Manual Therapy in the Treatment of Somatic Tinnitus
|
N/A |