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Tinnitus, Subjective clinical trials

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NCT ID: NCT03425045 Completed - Clinical trials for Tinnitus, Subjective

Repetitive Transcranial Magnetic Stimulation for Chronic Subjective Tinnitus

Start date: March 1, 2015
Phase: N/A
Study type: Interventional

Therapy of subjective chronic primary tinnitus could be challenging. Repetitive transcranial magnetic stimulation (rTMS) is currently being tested for suppressing the symptoms. However, effect of stimulation remains controversial. The aim was to uncover real effect of rTMS stimulation for tinnitus treatment. There will be three groups, stimulation group, sham stimulation group and controlled group with medicament treatment. The investigators assume that combination of rTMS stimulation of dorsolateral prefrontal cortex and primary auditory cortex at both sides will be more efficient. The investigators considered a 10% improvement in the tinnitus questionnaire score and in the tinnitus masking to be clinically relevant.

NCT ID: NCT03209297 Completed - Clinical trials for Tinnitus, Subjective

Temporomandibular Dysfunction in Patients With Tinnitus: Assessment and Treatment

Start date: March 27, 2017
Phase: N/A
Study type: Interventional

TMD treatment, based on state of the art knowledge derived from clinical studies will be applied in patients with tinnitus and TMD. When this approach proves to be useful for the treatment of tinnitus, it offers a new therapeutic option for patients with tinnitus. To understand how TMD treatment works for patients with tinnitus, we will analyse mediating factors, i.e. factors that contribute to the therapeutic effect. To help clinicians in their clinical process we will identify prognostic indicators, i.e. factors that predict a positive or negative outcome of TMD treatment. This can provide a helpful tool in clinical practice.

NCT ID: NCT02737670 Completed - Clinical trials for Tinnitus, Subjective

Sulodexide Efficacy in Chronic Idiopathic Subjective Tinnitus

SECIST
Start date: August 2014
Phase: Phase 2
Study type: Interventional

The objective of this prospective randomized and double blind controlled study is to evaluate the efficacy and safety of Sulodexide (25 mg) in the treatment of chronic idiopathic subjective tinnitus.

NCT ID: NCT02383147 Completed - Clinical trials for Tinnitus, Subjective

Efficacy Study for Development and Use of Neurofeedback-trainings for Patients Suffering From Chronic Tinnitus

Start date: March 2015
Phase: N/A
Study type: Interventional

Chronic tinnitus affects about 10-15% of the population in industrialized countries. Investigations of the brain activity by using electroencephalography (EEG) showed that in localized regions of the hearing system brain activity was decreased. This reduction of activity is thought to be one of the reasons that keep the perception of the tinnitus going. Recent studies have shown that neurofeedback is a viable option for treatment of chronic tinnitus. By using neurofeedback it is possible to train brain functions by the simple principle of rewarding wanted changes and punishing unwanted ones. The purpose of the investigators study is to show the efficacy of specific localized neurofeedback training in comparison to global relaxing neurofeedback training. In order to achieve decreased tinnitus symptoms or even disappearance of the tinnitus, 15 neurofeedback trainings are planned. Before and up to 6 month after the training EEG-recordings are performed.

NCT ID: NCT02315508 Completed - Clinical trials for Tinnitus, Subjective

Evaluating Possible Improvement in Tinnitus Severity After 28 Days Dosing of the Study Drug AUT00063 Compared to Placebo

QUIET-1
Start date: October 2014
Phase: Phase 2
Study type: Interventional

This study aims to demonstrate that the new medicine AUT00063 is effective and safe in the treatment of tinnitus.