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Clinical Trial Summary

This study evaluates the therapeutic effects of Etanercept (Enbrel) on the treatment of blast/noise induced tinnitus in adults. Half of the participants will receive 2 x 25mg/ Entanercept injections, and the other half will receive placebo injections.


Clinical Trial Description

The primary objectives are to test if: 1) Etanercept significantly reduces tinnitus distress as measured by Tinnitus Functional Index (TFI); and 2) Etanercept improves hearing. In addition, the investigators will test if: 1) Etanercept treatment leads to sustained therapeutic effects over time; The secondary objective is to test if: 1) Etanercept reduces tinnitus loudness measured by visual numeric scale (VNS) rating. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04066348
Study type Interventional
Source Wayne State University
Contact Jamal Chehab
Phone 313-577-5495
Email tinnitustrial@wayne.edu
Status Recruiting
Phase Phase 2
Start date July 1, 2022
Completion date September 2024

See also
  Status Clinical Trial Phase
Completed NCT02951715 - Improvement of Tinnitus After Oral Zinc on Patients With Noise-induced Hearing Loss N/A