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Tinea Corporis clinical trials

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NCT ID: NCT05881980 Not yet recruiting - Tinea Cruris Clinical Trials

Efficacy and Safety of Terbinafine and Itraconazole

Start date: May 2023
Phase: Phase 2/Phase 3
Study type: Interventional

There is a rise in the prevalence in recent years especially in tropical countries along with an increase in the number of treatment failures with chronic and recurrent dermatophytosis. There is a huge gap between the treatment required in the present scenario and the treatment guidelines given in the standard books. The aim of the study is to determine the effectiveness of terbinafine and itraconazole in different doses and in combination in the treatment of dermatophytosis. The study design will be a randomized parallel-group trial. Patients will be randomly divided into five parallel arms in which two of the standard drugs in recommended doses will be compared with their double doses and with a combination of both drugs. The patients will be reevaluated at 2, 4, 6, and 8 weeks of treatment (the end of therapy), using the physician Global Assessment (PGA) Scale. The cure will be considered a complete clinical resolution of the lesions. The patient's response to the treatment will be recorded. Safety and patient compliance will be recorded at each follow-up visit. Findings of observation will be recorded on a pre-prescribed and pre-tested data collection form. After collection, all data will be checked and compiled. Data will be processed and analyzed using computer software with statistical packages for social science SPSS-26. An analysis plan will be developed keeping in view the objectives of the study. The results of the continuous measurement will be presented on mean ± SD (mean-max) and results on categorical measurements will be presented in numbers (%). A p<0.05 will be considered statistically significant. Results will be disseminated to all Dermatology departments in Bangladesh.

NCT ID: NCT02767947 Completed - Tinea Corporis Clinical Trials

Safety and Efficacy of Product 33525 (Luliconazole Cream 1%) in Pediatric Participants With Tinea Corporis

Start date: February 8, 2016
Phase: Phase 4
Study type: Interventional

The objective of this study was to evaluate the safety, efficacy, and pharmacokinetics of luliconazole cream 1% when applied topically for 7 days in pediatric participants 2 years to 17 years of age (inclusive) with tinea corporis.

NCT ID: NCT02466867 Completed - Tinea Corporis Clinical Trials

An Open Label Pharmacokinetic Study of Naftin for Tinea Corporis

Start date: January 2014
Phase: Phase 4
Study type: Interventional

This is an open label, multi-center, multi-application pharmacokinetic study in pediatric subjects with tinea corporis.

NCT ID: NCT02227290 Completed - Tinea Corporis Clinical Trials

Pediatric Subjects With Tinea Corporis

Start date: August 2014
Phase: Phase 4
Study type: Interventional

The study is being done to see how well the study cream works when applied once a day to affected area of child (where they have ringworm). The results will be compared to those seen with a placebo cream which has no active ingredient. Safety of the cream will also be measured.

NCT ID: NCT01349998 Completed - Tinea Pedis Clinical Trials

Safety of a Topical Antifungal Treatment for Tinea Cruris, Tinea Pedis and Tinea Corporis

Start date: May 2011
Phase: Phase 3
Study type: Interventional

The purpose of this study is to examine the long-term safety of treating recurrent episodes of tinea pedis for 14 days for each recurrence and recurrent episodes of tinea corporis or tinea cruris for 7 days for each recurrence with Product 33525.

NCT ID: NCT01105013 Not yet recruiting - Tinea Pedis Clinical Trials

Evaluate the Efficacy and Safety of Tolnaftate Cream in the Treatment of Patients With Fungal Infections

Tonaftato
Start date: April 2012
Phase: Phase 3
Study type: Interventional

This is a study clinical, multicenter, Phase III trial, to evaluate the efficacy and safety of tolnaftate cream in the treatment of patients with fungal infections such as Tinea foot, Tinea and Tinea crural body.