Thyroidectomy Clinical Trial
Official title:
Development and Improvement of a Deep Convolutional Neural Network for Detection and Assessing the Perfusion of Parathyroid Gland During Endoscopic Thyroidectomy
Since the anatomical location and appearance of the parathyroid gland (PTG) vary, detection of the PTG and preserving the blood supply are among the difficulties encountered during a thyroidectomy procedure. We are planning to train a deep convolutional neural network based on a larger sample of endoscopic images to develop a model to assist surgeons in detection of PTG during endoscopic thyroidectomy. Furthermore, we would like to train a DCNN to predict blood perfusion based on endoscopic images comparing to indocyanine green fluorescence angiography as reference standard, and assess the performance of DCNN in predicting postoperative hypoparathyroidism.
Since the anatomical location and appearance of the parathyroid gland (PTG) vary, detection of the PTG and preserving the blood supply are among the difficulties encountered during a thyroidectomy procedure. Resection of the PTG by mistake or interruption of the blood supply may lead to transient or permanent hypoparathyroidism, which would require short-term or lifelong calcium and/or vitamin D supplement. We are planning to train a deep convolutional neural network based on a larger sample of endoscopic images to develop a model to assist surgeons in detection of PTG during endoscopic thyroidectomy. Although several researchers indicated that indocyanine green fluorescence angiography could be used to assess the perfusion of the PTG intraoperatively, it may cause allergic reaction and need repetitive injection. Therefore, we would like to train a DCNN to predict blood perfusion based on endoscopic images comparing to indocyanine green fluorescence angiography as reference standard, and assess the performance of DCNN in predicting postoperative hypoparathyroidism. This research may lead to the development of endoscopic modules in PTG detection and PTG perfusion prediction to reduce postoperative hypoparathyroidism. ;
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT02855866 -
Interest of Cryotherapy or Cortisone Aerosol Therapy in Early Post-operative Swallowing Disorders Following Total Thyroidectomy
|
N/A | |
Completed |
NCT05044351 -
Autofluorescence-guided Hemithyroidectomy in a Low-volume, Non-parathyroid Insitution: A Randomized Clinical Trial
|
N/A | |
Completed |
NCT05043584 -
Near-infrared Autofluorescence (NIRAF)-Guided Total Thyroidectomy: Impact in Low-volume, Non-parathyroid Institutions
|
N/A | |
Completed |
NCT04082845 -
Effect of Web-Based Training With Thyroidectomy Patients
|
N/A | |
Completed |
NCT04186715 -
Near Infrared Spectroscopy in Thyroidectomy
|
||
Not yet recruiting |
NCT02949856 -
E-T Tube Cuff Pressure Change After Changing Position From Neutral to Hyperextension of Neck
|
N/A | |
Completed |
NCT02136459 -
Non-neural Vocal Changes After Thyroidectomy
|
N/A | |
Withdrawn |
NCT03060499 -
Post Thyroidectomy Myocardial Function
|
||
Completed |
NCT03108742 -
Randomized Control Study of Dermal Staples vs Subcuticular Sutures on Postoperative Scar After Thyroidectomy
|
N/A | |
Completed |
NCT03035383 -
Purse String Suture for the Closure of Large Thyroidectomy Resulted in Better Cosmetics
|
N/A | |
Recruiting |
NCT06002984 -
Effectiveness of Intraoperative Neuromonitoring of External Branch of Superior Laryngeal Nerve in Thyroid Surgery
|
N/A | |
Recruiting |
NCT06162390 -
Optimal Concentration of Remifentanil for NIM Tube Intubation With Low-dose NMBA
|
N/A | |
Recruiting |
NCT04481893 -
Interest of the Virtual Reality Headset in the Management of Perioperative Stress in Patients Candidates for Total Thyroidectomy
|
N/A | |
Completed |
NCT02577068 -
Combination Effect of Nefopam With Propacetamol for Postoperative Pain After Thyroidectomy
|
N/A | |
Completed |
NCT03349294 -
Clinical Study of Biokinetic Model of Iodine-131 in Total(Near) Thyroidectomy Patients.
|
||
Recruiting |
NCT05851560 -
Prospective Comparison of the Effect on Antiadhesive Barriers During Thyroid or Parathyroid Surgery
|
Phase 1 | |
Completed |
NCT02768753 -
Comparison Between the Axillary Bilateral-breast Approach (ABBA) and Bilateral Axillo-breast Approach (BABA) for Robotic Thyroidectomy
|
N/A | |
Recruiting |
NCT05642741 -
Validation of a Hypoparathyroidism Self-questionnaire
|
||
Withdrawn |
NCT02568085 -
Trial Evaluating Use of Arista in Total Thyroidectomy
|
N/A | |
Recruiting |
NCT01607242 -
Impact of Total Thyroidectomy on Voice and Swallowing
|
N/A |