Effect of Head Position During Thyroidectomy on Postoperative Cognitive Functions

Thyroid Clinical Trial

Official title:

The Effect of Head Position During Thyroidectomy on Cerebral Oxygenation and Postoperative Cognitive Functions

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04830293
• Other study ID #: 2119-40-14/02
• Status: Completed
• Start date: March 1, 2019
• Est. completion date: December 31, 2020

Study information

• Verified date: April 2021
• Source: Zonguldak Bulent Ecevit University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational [Patient Registry]

Clinical Trial Summary

The aim of our study is to observe the effect of head-neck position of patients scheduled for thyroidectomy, on carotid artery blood flow, regional cerebral oxygen saturation measured using near-infrared spectroscopy technology, and postoperative cognitive dysfunction.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 1
• Est. completion date: December 31, 2020
• Est. primary completion date: October 30, 2020
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 50 Years

Eligibility

Inclusion Criteria:

• undergo a total thyroidectomy operation

• ASA I-II

• euthyroid patients in the preoperative period

Exclusion Criteria:

• Hemoglobin< 8 g / dl

• Hypertension

• Hyperlipidemia

• Pregnancy

• Patients diagnosed with diabetes mellitus

• Cerebrovascular insufficiency

• Known carotid artery lesion

• Metabolic diseases

• Any intracranial pathology present

• Surgeries exceeding 180 minutes

Related Conditions & MeSH terms

• Carotid Doppler
• Cerebral Perfusion
• Thyroid

Intervention

Procedure:
• Carotis Doppler Ultrasound
Neck was rotated about 30-45 ° to the opposite side of the image. The common carotid artery and internal jugular vein were viewed transversely on the B Mode USG image. Then, the probe was rotated approximately 90 ° and the carotid artery was visualized in the longitudinal plane. The probe and guide line were adjusted so that the Doppler angle was 60 °. The image was created with the guiding line parallel to the blood flow. After imaging of the carotid artery bifurcation, measurements were made 1 cm distal to this level.

Locations

Country	Name	City	State
Turkey	Zonguldak Bülent Ecevit University Medicine Faculty	Zonguldak	Kozlu

Sponsors (1)

Lead Sponsor	Collaborator
Zonguldak Bulent Ecevit University

Country where clinical trial is conducted

Turkey, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Changes in cognitive functions	determine cognitive dysfunction using mini mental state examination	3 months after surgery
Secondary	Changes in Cerebral Perfusion	Changes in main carotid artery blood flow and cerebral oxygenation by using carotid doppler	during surgery