Hemodynamic Parameters in Euthyroid Patients With Thyroid Nodules

Thyroid Nodules Clinical Trial

Clinical Trial Details — Status: Terminated

Administrative data

• NCT number: NCT00507897
• Other study ID #: ESheverdova-1
• Status: Terminated
• Phase: N/A
• First received: July 25, 2007
• Last updated: February 6, 2008
• Est. completion date: December 2007

Study information

• Verified date: February 2008
• Source: Yaroslavl State Medical Academy
• Contact: n/a
• Is FDA regulated: No
• Health authority: Russia: Ethics Committee
• Study type: Observational

Clinical Trial Summary

The purpose of this study is to determine the relationship of hemodynamic parameters with the level of thyroid hormones and the histological structure of thyroid nodules in euthyroid patients.

Description:

As opposed to widely investigated condition of cardiovascular system in patients with functional disorders of thyroid gland, the relationship between thyroid hormones and hemodynamic parameters in euthyroid patients remains not enough clear.

We detect the parameters of blood pressure and thyroid hormones in euthyroid patients with thyroid nodules directly before planned operation on the thyroid gland.

As the study is carries out directly before operation, that assumes presence of preoperative stress in patients, activity of the sympatho - adrenal system is estimated in addition.

On the one hand, the design of our research will allow to estimate relationship of thyroid hormones with the parameters of blood pressure in conditions of euthyroidism, on the other hand - to investigate features of blood pressure in patients with thyroid nodules.

The research of the patients in the preoperative period will enable to select the group of patients without pathology of cardiovascular system whose increased blood pressure is connected with preoperative stress, that in turn will allow to exclude influence of the pathology of the cardiovascular system on studied correlation.

Recruitment information / eligibility

• Status: Terminated
• Enrollment: 100
• Est. completion date: December 2007
• Accepts healthy volunteers: No
• Gender: Both
• Age group: N/A and older

Eligibility

Inclusion Criteria:

• Euthyroid patients with thyroid nodules before operation on the thyroid gland

Exclusion Criteria:

• Hyperthyroidism

• Hypothyroidism

Study Design

Time Perspective: Prospective

Related Conditions & MeSH terms

• Thyroid Diseases
• Thyroid Nodule
• Thyroid Nodules

Locations

Country	Name	City	State
Russian Federation	Yaroslavl State Medical Academy	Yaroslavl

Sponsors (1)

Lead Sponsor	Collaborator
Yaroslavl State Medical Academy

Country where clinical trial is conducted

Russian Federation,