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Thyroid Nodule clinical trials

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NCT ID: NCT05658809 Not yet recruiting - Thyroid Nodule Clinical Trials

Intervention in Single Thyroid Nodule.

Start date: December 30, 2022
Phase: N/A
Study type: Interventional

Thyroid nodules are common clinical problem. The incidence is 2-4 per 100,000 people per year, being more common in women and the elderly. thyroid nodule is a "discrete lesion within the thyroid gland that is radiologically distinct from the surrounding thyroid parenchyma. Most thyroid nodules are asymptomatic, may present as neck swelling

NCT ID: NCT05428371 Not yet recruiting - Thyroid Cancer Clinical Trials

Assessment the Cancer Risk of Indeterminate Thyroid Nodules Through Integration of Clinical, Ultrasonographic and Multiomic Features

THYOMICS
Start date: January 1, 2023
Phase:
Study type: Observational

Indeterminate thyroid nodules have a mild risk of malignancy (15-30%). The aim of our study is to individuate new biomarkers of thyroid carcinoma through multiomic analyses of blood samples and of specimen samples of patients with indeterminate thyroid nodules.

NCT ID: NCT05407506 Not yet recruiting - Thyroid Nodule Clinical Trials

Clinical Study of Ultrasonic Artificial Intelligence and Fine Needle Aspiration in Qualitative Diagnosis of Thyroid Nodules

Start date: June 2022
Phase: N/A
Study type: Interventional

To study the value of thyroid artificial intelligence diagnosis system and fine needle puncture in the diagnosis of benign and malignant thyroid nodules, so as to provide evidence-based medical evidence for the diagnosis of benign and malignant thyroid nodules by artificial intelligence.

NCT ID: NCT05323669 Not yet recruiting - Thyroid Cancer Clinical Trials

Molecular Profile of Thyroid Nodules

MPTN
Start date: April 11, 2022
Phase:
Study type: Observational

Profiling and comparative analysis of genomic alterations and miRNA expression in benign and malignant thyroid tumors using histological and cytological specimens will be performed. Obtained information is necessary to create a molecular test to refine the cancer risk of cytologically indeterminate thyroid nodules.

NCT ID: NCT05216718 Not yet recruiting - Thyroid Nodule Clinical Trials

Mini-flap BABA (Bilateral Axillo-breast Approach) Robotic Thyroidectomy is Safe

Start date: January 24, 2022
Phase: N/A
Study type: Interventional

In this study, a randomized controlled study was conducted between two groups of 40 recipients of conventional flap during BABA robotic-thyroidectomy and 40 recipients of Mini-flap method during BABA robotic-thyroidectomy. In this study, we tried to determine whether the use of Mini-flap can reduce sensory loss and pain after BABA robotic-thyroidectomy.

NCT ID: NCT04580199 Not yet recruiting - Thyroid Nodule Clinical Trials

Surgical Versus Non Surgical Management of Thyroid Nodule

Start date: December 1, 2020
Phase: N/A
Study type: Interventional

To compare between surgical (hemi thyroidectomy and total thyroidectomy) and non-surgical (medical, ethanol injection,thermal ablation and laser photo coagulation) management of simple thyroid nodule regarding: - Outcome of every type of management - Feasibility of minimally invasive technique in management of simple thyroid nodule in Asyut university - Complication of every type of management

NCT ID: NCT04312646 Not yet recruiting - Thyroid Nodule Clinical Trials

Elastography in Thyroid Nodules

Start date: April 1, 2020
Phase:
Study type: Observational

Thyroid nodules are a common finding in the general population,however, they are mostly unpalpable and usually discovered either during neck ultrasound (US) examination or by pathological examination at autopsy. They are found in about 8% of adults. Most thyroid nodules ''incidentalomas" are benign, however 7% may be malignant. Early detection of thyroid cancer helps in early treatment and better survival US is an accurate method for detection of thyroid nodules; however, US has a low accuracy in differentiating between benign from malignant thyroid nodules . US could suggest a malignancy likelihood criteria of a thyroid nodule, such as hypoechogenicity, increased intranodular vascularity, irregular margins, microcalcifications, absent halo, and a taller-than-wide shape measured in the transverse dimension.

NCT ID: NCT04298684 Not yet recruiting - Clinical trials for Diabetes Mellitus, Type 2

Efficacy of Metformin Versus Sitagliptin on Benign Thyroid Nodules in Type 2 Diabetes

METNODTHYR
Start date: January 1, 2021
Phase: Phase 4
Study type: Interventional

A 2-years prospective, randomized and multicentric study will be performed to assess the efficacy of metformin compared to sitagliptin on benign thyroid nodules size ≥ 2 cm, in newly diagnosed patients with type 2 diabetes.

NCT ID: NCT04233398 Not yet recruiting - Clinical trials for Thyroid Nodule (Benign)

HIFU Treatment of Benign Thyroid Nodules

Start date: August 2024
Phase: N/A
Study type: Interventional

This clinical trial is to evaluate the effectiveness and the safety of high intensity focused ultrasound (HIFU) in the treatment of benign thyroid nodules.

NCT ID: NCT03884140 Not yet recruiting - Thyroid Nodule Clinical Trials

Clinical Diagnostic Approach for Cases of Thyroid Nodules

Start date: September 1, 2019
Phase:
Study type: Observational [Patient Registry]

Thyroid nodules are a common presentation in the clinic, with an increasing incidence, especially in women. Their clinical significance is mainly related to excluding malignancy (4.0 to 6.5% of all thyroid nodules).