Thyroid Neoplasms Clinical Trial
Official title:
Phase 2 Study of the Anti-Angiogenesis Agent AG-013736 in Patients With Metastatic Thyroid Cancer Who Are Refractory to or Not Suitable Candidates for 131 I Treatment
This is a Phase 2 study being conducted at multiple centers in the United States. Patients having thyroid cancer that has spread to other parts of the body (i.e., metastatic) are eligible to participate. Patients must have disease that was not controlled by previous treatment with radioactive iodine (131I) or not be good candidates for such treatment. The purpose of the study is to test whether the angiogenesis inhibitor AG-013736 is an effective treatment for metastatic thyroid cancer as shown by the number of patients in the study who experience significant and durable tumor shrinkage.
n/a
Allocation: Non-Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT00537095 -
Efficacy and Safety of Vandetanib (ZD6474) in Patients With Metastatic Papillary or Follicular Thyroid Cancer
|
Phase 2 | |
Recruiting |
NCT04139096 -
Genetic Susceptibility to Radiation Induced Thyroid Cancer
|
||
Completed |
NCT00754182 -
Subcuticular Suture Versus Synthetic Glue in Thyroidectomy Incision
|
N/A | |
Completed |
NCT00148213 -
Clinical Evaluation of a New Highly Sensitive Thyroglobulin Assay in Differentiated Thyroid Carcinoma
|
N/A | |
Recruiting |
NCT06398795 -
Dual-port Trans-subclavian Thyroid Endoscopic Surgery
|
N/A | |
Recruiting |
NCT01005654 -
Prospective Comprehensive Molecular Analysis of Endocrine Neoplasms
|
||
Active, not recruiting |
NCT05579782 -
Assessing Benefits of NIRAF Detection for Identifying Parathyroid Glands During Total Thyroidectomy
|
N/A | |
Completed |
NCT01437254 -
To Compare Safety and the General Imaging Pattern of Cyclotron Produced Technetium vs. Generator Produced Technetium in Patients With Thyroid Cancer
|
Phase 1 | |
Recruiting |
NCT03160274 -
Genetic Analysis of Pheochromocytomas, Paragangliomas and Associated Conditions
|
||
Completed |
NCT00984282 -
Nexavar® Versus Placebo in Locally Advanced/Metastatic RAI-Refractory Differentiated Thyroid Cancer
|
Phase 3 | |
Completed |
NCT01292044 -
The Role of Elastography in the Diagnosis of Thyroid Nodules
|
N/A | |
Terminated |
NCT04644315 -
A Home-Based Approach Study to Evaluate the Efficacy and Safety of Alectinib in Locally-Advanced or Metastatic ALK-Positive Solid Tumors
|
Phase 2 | |
Active, not recruiting |
NCT02418247 -
Minimize Radioactive Iodine Ablation Of Remnant Thyroid in Differentiated Thyroid Cancer
|
Phase 2/Phase 3 | |
Completed |
NCT00467506 -
Phase II Two-step Radioimmunotherapy Clinical Study in Medullary Thyroid Carcinoma
|
Phase 2 | |
Completed |
NCT02430714 -
Post-marketing Surveillance of Lenvatinib Mesylate (Lenvima Capsule) in Patients With Unresectable Thyroid Cancer (Study LEN01T)
|
||
Recruiting |
NCT04396912 -
Post-thyroidectomy Vocal Cord Paralysis Along With Hypocalcemia: STROBE - Guided Prospective Cohort
|
||
Enrolling by invitation |
NCT04411290 -
Malignancy Predictors, Bethesda and TI-RADS Scores Correlated With Final Histopathology in Thyroid Diseases
|
||
Recruiting |
NCT04410601 -
Post-thyroidectomy Dysphagia: An International Multicentric CONSORT - Compatible RCT
|
N/A | |
Completed |
NCT03469310 -
Minimizing Narcotic Analgesics After Endocrine Surgery
|
Phase 4 | |
Completed |
NCT03871387 -
The Effects of Deep Neuromuscular Blockade During Robot-assisted Transaxillary Thyroidectomy on Postoperative Pain and Sensory Change
|
N/A |