Thyroid Profiles in Patients With Acute Illness

Status Recruiting

Clinical Trial Summary

Patients admitted to the hospital with acute illness may have a wide spectrum of thyroid function abnormalities. It is largely unknown whether such aberrations are temporary or persist for a long time, and whether they impact prognosis of such patients.

Clinical Trial Description

Recently, there has been a growing body of evidence that subclinical thyroid dysfunction as a contributor to the increase of cardiovascular events. Elevated serum thyroid-stimulating hormone (TSH) levels and normal free thyroxine (FT4) and free triiodothyronine (FT3) levels have been associated with worse heart failure and dyslipidemia. Furthermore, higher risk of atrial fibrillation has been linked tp thyroid abnormalities in these patients. Patients admitted to the hospital with acute illness may have a wide spectrum of thyroid function abnormalities. It is largely unknown whether such aberrations are temporary or persist for a long time, and whether they impact prognosis of such patients. This study aimed at evaluating the prevalence of thyroid function abnormalities in patients admitted to hospital with acute illness and their temporal changes and impact on mortality during hospitalization and at 1 year. Serum level of thyroid stimulating hormone and free T4 and T3 measured on admission. Clinical and laboratory profiles of patients with abnormal thyroid function (ATF group) will be compared to those with normal thyroid function (NTF group). Short and long term survival of both groups were compares as well. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05980923
Study type	Observational
Source	Jordan Collaborating Cardiology Group
Contact	Ayman J Hammoudeh, MD, FACC
Phone	0096265001000
Email	a.hammoudeh@istisharihospital.com
Status	Recruiting
Phase
Start date	October 15, 2023
Completion date	October 30, 2024

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