Function Integrity of Neck Anatomy in Thyroid Surgery

Status Recruiting

Clinical Trial Summary

Recent trends in the management of patients with low-risk papillary thyroid carcinoma who have a nonsuspicious or cytologically benign contralateral nodule call into question the need for routine total thyroidectomy. Although the lobectomy for the unilateral thyroid cancer with contralateral benign nodules is sufficient treatment, some of the patients might suffer from the anxiety of the residual benign thyroid nodule and tend to choose total thyroidectomy, which might be overtreatment. Thermal ablation has been proven to be effective in achieving nodule shrinkage and being also free from major complications. In our institution, intraoperative RFA was a proposed alternative strategy to treat the contralateral benign nodules after the thyroid lobectomy for the malignant lobe, which was found to have a better quality of life on anxiety, physiological health, social family, psychological and sensory mentions with a considerable complication rate.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04666103
Study type	Interventional
Source	Wuhan University
Contact	Qianqian Yuan, M.D.
Phone	13026322297
Email	Yuanqq11@whu.edu.cn
Status	Recruiting
Phase	N/A
Start date	December 11, 2020
Completion date	December 12, 2026

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT02658513` - Evaluation of Lancet Blood Sampling for Radioiodine Dosimetry in Thyroid Cancer
Withdrawn	`NCT01707056` - The Effect of Coffee on the Absorption of Thyroid Hormone in Patients With Thyroid Carcinoma	N/A
Completed	`NCT00215605` - Study of XL184 (Cabozantinib) in Adults With Advanced Malignancies	Phase 1
Terminated	`NCT04327999` - Effect of Artificial Tears on Radioiodine Levels in the Nasolacrimal Duct System	Phase 2
Completed	`NCT02194920` - Parathyroid Reimplantation in Forearm Subcutaneous Tissue During Thyroidectomy: a Simple Way to Avoid Ipoparathyroidism and Evaluate Graft Function	N/A
Enrolling by invitation	`NCT06095362` - Thyroid Cancer and Central Lymph Node Metastases Detection Using Bevacizumab-IRDye800CW	Phase 1
Not yet recruiting	`NCT05949424` - OPTI - DOSE: Optimal Dosing of Oral Anticancer Drugs in Older Adults	Phase 4
Active, not recruiting	`NCT02145143` - Enhancing Radioiodine (RAI) Incorporation Into BRAF Mutant, RAI-Refractory Thyroid Cancers With the BRAF Inhibitor Vemurafenib: A Pilot Study	N/A
Terminated	`NCT01865838` - A Study Into the Effect of Seprafilm in Open Total Thyroidectomy	N/A
Recruiting	`NCT00749697` - Radioiodine Dosimetry Protocol for Thyroid Cancer Metastases	N/A
Enrolling by invitation	`NCT04411290` - Malignancy Predictors, Bethesda and TI-RADS Scores Correlated With Final Histopathology in Thyroid Diseases
Completed	`NCT01813136` - Phase II Study of the Optimal Scheme of Administration of Pazopanib in Thyroid Carcinoma	Phase 2
Recruiting	`NCT05668962` - Restor. I-131 Upt. + Selpercatinib in RET F-P RAI-R TC	Phase 2
Active, not recruiting	`NCT02185560` - Prospective, Non-interventional, Post-authorization Safety Study That Includes All Patients Diagnosed as Unresectable Differentiated Thyroid Carcinoma and Treated With Sorafenib
Completed	`NCT04462471` - Vemurafenib Plus Copanlisib in Radioiodine-Refractory (RAIR) Thyroid Cancers	Phase 1
Completed	`NCT01433809` - Biomarkers to Distinguish Benign From Malignant Thyroid Neoplasm	N/A
Recruiting	`NCT00929318` - Influence of Thyroid Hormones on the Woundhealing Process	N/A
Completed	`NCT05178186` - Impact of the COVID-19 Pandemic on Surgery for Thyroid Cancer	N/A
Completed	`NCT02773667` - Renal Tracer Elimination in Thyroid Cancer Patients Treated With 131-Iodine
Not yet recruiting	`NCT00993837` - Feasibility of Endoscopic Thyroidectomy for Thyroid Carcinoma	N/A