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Thyroid Cancer, Follicular clinical trials

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NCT ID: NCT05796960 Recruiting - Thyroid Cancer Clinical Trials

European Multicenter Study on Surgical Management of Advanced Thyroid Cancer

ATCEU
Start date: December 15, 2022
Phase:
Study type: Observational

The main aim of the study is to evaluate peri-operative surgical characteristics, operation extent, postoperative morbidity, and outcomes in patients undergoing surgery for advanced thyroid cancer in different European centers using the EUROCRINE® database.

NCT ID: NCT04544111 Active, not recruiting - Thyroid Cancer Clinical Trials

PDR001 Combination Therapy for Radioiodine-Refractory Thyroid Cancer

Start date: September 2, 2020
Phase: Phase 2
Study type: Interventional

The purpose of this study is to find out whether a drug called PDR001, combined with either trametinib or dabrafenib, is a safe and effective treatment for thyroid cancer.

NCT ID: NCT04462471 Completed - Thyroid Cancer Clinical Trials

Vemurafenib Plus Copanlisib in Radioiodine-Refractory (RAIR) Thyroid Cancers

Start date: June 26, 2020
Phase: Phase 1
Study type: Interventional

The purpose of this study is to develop a new drug treatment to reverse tumor resistance to radioiodine in BRAF mutant tumors so that radioiodine can be given to shrink tumors. This study is also being done to find out the highest doses of copanlisib and vemurafenib that, when given in combination, do not cause serious side effects, and whether the study treatment will make radioiodine therapy work better in patients with BRAF-mutant thyroid cancers.