Thrombophilia Clinical Trial
Official title:
Arterial Microcirculation, Macrocirculation and Thrombophilias
Rationale: To analyse the arterial state of women with thrombophilia by techniques studying
micro and arterial macrocirculation because of a reported and still discussed increase risk
in cardio-vascular events in these women.
Primary objective: To measure endothelium dependent vasodilatation (VDE) in controls and in
women with thrombophilia.
There are several papers reporting an increase in the risk of arterial diseases in women
with thrombophilia. However these reports remain controversial. In order to gain insight on
that issue we propose to study the micro and macrocirculation in women with an history of
venous thrombosis or thrombophilia and in controls matched by age.
Design: It is a prospective open transversal trial.
Management of the study: Two groups of 80 women will be compared: healthy volunteers and
women with thrombophilia. Following an inclusion consultation where the informed consent
will be obtained and inclusion criteria checked, an appointment for the arterial
explorations will be given. These explorations will be measurement of endothelium dependent
vasodilatation (EDV), capillar density, arterial fitness and compliance and retinogram.
There is no follow-up visit.Benefits and risks: the measurement will characterize the
arterial state of patients with thrombophilia included in the study.There is no risk in
performing these techniques.
Principal criteria: measurement of EDV.
Secondary criteria: capillar density, arterial compliance and stiffness and retinogram.
;
Observational Model: Case Control, Time Perspective: Cross-Sectional
Status | Clinical Trial | Phase | |
---|---|---|---|
Recruiting |
NCT04398628 -
ATHN Transcends: A Natural History Study of Non-Neoplastic Hematologic Disorders
|
||
Completed |
NCT03682419 -
Evaluation of Precision and Accuracy of INR Measurements in a Point of Care Device (OPTIMAL)
|
N/A | |
Recruiting |
NCT05551078 -
Thrombophilia Screening After Severe IUGR
|
||
Completed |
NCT02139670 -
Thrombin Generation and Gestational Outcome
|
N/A | |
Completed |
NCT01416454 -
Thromboelastography to Assess Age-Related Coagulation Differences in Patients Undergoing Cesarean Delivery
|
N/A | |
Completed |
NCT01372553 -
Guilford Genomic Medicine Initiative (GGMI)
|
Phase 4 | |
Terminated |
NCT00356434 -
A Comparison of Sequential Compression Devices and Foot Pumps in the Obstetric Population
|
N/A | |
Completed |
NCT01214772 -
The Effect of Heparin in Treatment IVF-ET Failure
|
Phase 4 | |
Completed |
NCT00967382 -
TIPPS: Thrombophilia in Pregnancy Prophylaxis Study
|
Phase 3 | |
Recruiting |
NCT06171984 -
Thrombophilia Assessment Under DOAC: Effectiveness of Activated Charcoal
|
||
Completed |
NCT02407730 -
EFFects of Thrombophilia on the Outcomes of Assisted Reproduction Technologies
|
||
Completed |
NCT01487291 -
Prevalence of Clinical and Laboratory Markers of Hypofibrinolysis in Psychotic Patients
|
N/A | |
Completed |
NCT00883272 -
Effect of DT56a (Femarelle) on the Coagulation System in the Treatment of Postmenopausal Women
|
||
Unknown status |
NCT01486511 -
Pulmonary Embolism After Liver Resection
|
N/A | |
Completed |
NCT00457184 -
Thrombophilia and Migraine, Are They Related?
|
N/A | |
Recruiting |
NCT05853796 -
Observational Dutch Young Symptomatic StrokE studY - nEXT
|
||
Completed |
NCT05225155 -
Effect of Prophylatic Use of Enoxaparin in Women Undergoing in Vitro Fertilization Treatment
|
||
Enrolling by invitation |
NCT01905748 -
Acute Phase Reactions and Thrombophilia in Pediatric Patients With Migraine
|
N/A | |
Recruiting |
NCT04519398 -
Investigating the Involvement of ACE and Angiotensinogen Genes' Polymorphism Along With Other Thrombophilic Genotypes in Severe Forms of COVID-19 With/Without Thrombotic Events
|
||
Active, not recruiting |
NCT04537416 -
Fertility, Hypercoagulability, and Inflammation (FREYA) Registry
|