Platelet Kinetics After Platelet Transfusion for the Placement of a Central Venous Catheter

Thrombopenia Clinical Trial

— PLATCAT  

Official title:

Evaluation of the Effectiveness and Security of the Prophylactic Platelet Transfusion in Thrombocytopenic Patients Requiring the Placement of a Central Venous Catheter

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT02906878
• Other study ID #: 2015-AO1924-45
• Status: Recruiting
• Phase: N/A
• First received: July 5, 2016
• Last updated: September 19, 2016
• Start date: June 2016
• Est. completion date: July 2017

Study information

• Verified date: September 2016
• Source: University Hospital, Angers
• Contact: Nicolas LEROLLE, MD PhD
• Phone: +33241353478
• Email: NiLerolle[@]chu-angers.fr
• Is FDA regulated: No
• Health authority: FRANCE : ANSM
• Study type: Observational

Clinical Trial Summary

PLATCAT study's purpose is to evaluate platelet kinetics after platelet transfusion

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 30
• Est. completion date: July 2017
• Est. primary completion date: July 2017
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Admission en haematology unit

• Need for a central venous catheter

• Thrombopenia < 50 G/L

Exclusion Criteria:

• Patient protected by law

• Pregnant or breastfeeding women

• Peripheral thrombopenia

• Patient admitted in Intensive Care Unit

Study Design

Observational Model: Case-Only, Time Perspective: Prospective

Related Conditions & MeSH terms

• Central Venous Catheter Placement
• Thrombocytopenia
• Thrombopenia

Intervention

Procedure:
• Platelets transfusion
Prophylactic platelet transfusion in thrombocytopenic patients for the placement of a central venous catheter

Locations

Country	Name	City	State
France	University Hospital	Angers

Sponsors (1)

Lead Sponsor	Collaborator
University Hospital, Angers

Country where clinical trial is conducted

France, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	72 hours thrombocythemia kinetics after a platelet transfusion	Blood drawing a H-1:00, H+0:10, H+1:00, H+4:00, H+24h00, H+72:00 Evaluation of platelets count on sodium citrate tube.	72 hours post transfusion	No
Secondary	Transfusion Safety - assessed by Troubles during process	Troubles during process (pneumothorax, laying failure, hematoma) Hematoma at H+24:00 Immunisation anti HLA,HPA	One day after transfusion	No
Secondary	Transfusion Efficacy	Number of blood or platelets transfusion	One month after transfusion	No
Secondary	Description of patients treatment	Type of received chemotherapy	One week before and one month after transfusion	No