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Thrombocytopenia clinical trials

View clinical trials related to Thrombocytopenia.

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NCT ID: NCT04100876 Not yet recruiting - Clinical trials for Primary Immune Thrombocytopenia

Effect of DNMT SNPs on DNA Methylation in Primary ITP

Start date: December 1, 2019
Phase:
Study type: Observational

- To compare global DNA methylation status between ITP patients and healthy subjects . - To determine the effect of DNMT3A −448 G/A SNP variant A allele and DNMT3B −149C/T SNP variant T-allele on global DNA methylation in both ITP patients and healthy control subjects.

NCT ID: NCT04094805 Not yet recruiting - Clinical trials for Immune Thrombocytopenia

A Multicenter Randomized Study of Vitamin D Combined With HD-DXM Versus HD-DXM for the Treatment of ITP

Start date: October 1, 2020
Phase: Phase 4
Study type: Interventional

The project was undertaking by Qilu Hospital of Shandong University in China. In order to report the efficacy and safety of vitamin D combining with high-dose dexamethasone for the treatment of adults with newly-diagnosed primary immune thrombocytopenia (ITP).

NCT ID: NCT03912129 Not yet recruiting - Evans Syndrome Clinical Trials

Autoimmune Cytopenia: Genetics and Pathophysiological Mechanism in Pediatric Evans Syndrome

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Start date: May 6, 2019
Phase: N/A
Study type: Interventional

Characterization of the genetic causes, and of the immunopathological clinical and biological manifestations in children with pediatric Evans syndrome included in a prospective national observational cohort of rare diseases.

NCT ID: NCT03838354 Not yet recruiting - Thrombocytopenia Clinical Trials

A Clinical Trial of the Low Dose Chidamide in the Management of Refractory ITP

Start date: June 1, 2019
Phase: Phase 2
Study type: Interventional

Nowdays HDACi's were more and more focused on the anti-inflammatory and immunomodulatory activities,independent of their known proapoptotic or cell cycle arrest actions on malignant cells. Low concentrations of HDACi's are effective in reducing inflammation and autoimmune response in humans with juvenile idiopathic arthritis and animal models of inflammatory bowel disease and arthritis. The project was undertaking by Qilu Hospital of Shandong University in China. In order to report the efficacy and safety of the low dose chidamide in the management of refractory ITP.

NCT ID: NCT03823079 Not yet recruiting - Clinical trials for Recurrent Colorectal Carcinoma

Comparison of Interleukin-11 and rhTPO for Recurrent Colorectal Cancer Patients With Thrombocytopenia

Start date: February 1, 2019
Phase: Phase 2
Study type: Interventional

This randomized controlled clinical phase II study was designed to compare the effect of rhTPO with rhIL-11 in improving thrombocytopenia in patients with recurrent colorectal cancer who underwent radiotherapy and with thrombocytopenia.

NCT ID: NCT03692754 Not yet recruiting - Clinical trials for Immune Thrombocytopenia

Atorvastatin in Management of Newly Diagnosed ITP

Start date: November 1, 2021
Phase: Phase 2/Phase 3
Study type: Interventional

The project was undertaking by Qilu Hospital of Shandong University in China. In order to report the efficacy and safety of atorvastatin for the treatment of adults with immune thrombocytopenia (ITP).

NCT ID: NCT03492515 Not yet recruiting - Clinical trials for Immune Thrombocytopenia

Recombinant Human Thrombopoietin(rhTPO) in Pregnancy With Immune Thrombocytopenia

Start date: May 1, 2018
Phase: Phase 3
Study type: Interventional

The purpose of this study was to observe the clinical efficacy and adverse reactions of rhTPO in the treatment of pregnancy-induced thrombocytopenia.

NCT ID: NCT03460808 Not yet recruiting - Clinical trials for Immune Thrombocytopenia

The Combination of Atorvastatin, Acetylcysteine and Danazol as the Treatment of Steroid-resistant/Relapse Immune Thrombocytopenia

Start date: March 10, 2018
Phase: Phase 1/Phase 2
Study type: Interventional

Single-arm, open-lable, multicentre study to compare the efficacy and safety of atorvastatin, acetylcysteine plus danazol with danazol monotherapy in patients with corticosteroidresistant/relapsed ITP.

NCT ID: NCT03448952 Not yet recruiting - Clinical trials for Thrombocytopenia Neonatal

Neonatal Thrombocytopenia Among Newborns Admitted to Neonatal Intensive Care Unit

Start date: March 2019
Phase: N/A
Study type: Observational

Thrombocytopenia is diagnosed when platelet count is lower than 150,000 U/L, it is a common hemostatic problem in neonatal intensive care units According to platelets count, it is classified into mild thrombocytopenia with platelet count 100,000 to 150,000 U/L, moderate thrombocytopenia with platelet count 50,000 to 100,000 U/L and severe thrombocytopenia that have platelet count less than or equal to 50,000 U/L.

NCT ID: NCT03443570 Not yet recruiting - Clinical trials for Immune Thrombocytopenia

Rituximab Combining Bortezomib Versus Rituximab in Management of ITP

Start date: March 1, 2018
Phase: Phase 3
Study type: Interventional

The project was undertaking by Qilu Hospital of Shandong University and other 2 well-known hospitals in China. In order to report the efficacy and safety of rituximab combining with bortezomib for the treatment of adults with immune thrombocytopenia (ITP), compared to rituximab alone .