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Throat Carcinoma clinical trials

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NCT ID: NCT05420948 Recruiting - Clinical trials for Head and Neck Cancer

A Study of Pembrolizumab in Combination With Chemotherapy for Head and Neck Cancer

Start date: October 17, 2022
Phase: Phase 2
Study type: Interventional

By doing this study, the research team would like to learn if using a blood test that measures the amount of tumor DNA in blood can help guide how to use chemotherapy combined with immunotherapy for individuals with head and neck cancer. Using this blood test, the research team hopes to learn if intermittent (occasional) chemotherapy added to immunotherapy will work better than immunotherapy alone. Participation in this research will last about two years.

NCT ID: NCT04444869 Recruiting - Oropharynx Cancer Clinical Trials

Testing Less Intensive Radiation With Chemotherapy to Treat Low-risk Patients With HPV-positive Oropharyngeal Cancer

ENID
Start date: September 28, 2020
Phase: Phase 2
Study type: Interventional

This trial will explore giving standard dose chemotherapy and radiation therapy to sites of disease including all lymph nodes involved with HPV-positive oropharyngeal cancer, but administer lower doses of radiation therapy to the lymph nodes that are not known to be involved with cancer. By doing so, it is hypothesized that there will be equally good long term loco-regional and distant disease control but will reduced long term treatment side effects and improved quality of life in persons living well beyond their cancer treatment.

NCT ID: NCT04003051 Recruiting - Throat Carcinoma Clinical Trials

Web-Based Program in Helping Patients With Head and Neck Cancer Adhere to Swallowing Exercises and Coping Strategies

Start date: March 18, 2019
Phase: Phase 2
Study type: Interventional

This phase II trial studies how well a web-based program called Project Prepare works in helping patients with head and neck cancer adhere to swallowing and trismus exercises and coping strategies. Head and neck cancer patients who receive radiation therapy are at risk for permanent swallowing disorders and other side effects. Because of these potential problems, swallowing exercises and coping strategies are important parts of recovery. A web-based program designed to increase adherence to preventive exercises may help patients with head and neck cancer ameliorate the long-term effects of radiation therapy.