Thoracotomy Clinical Trial
Official title:
The Analgesic Value of Paravertebral Calcitonin in Patients Undergoing Thoracotomy
This prospective randomized double-blinded controlled study will be conducted to evaluate the effect of adding calcitonin to bupivacaine in thoracic paravertebral block for patients undergoing thoracotomy.
Status | Recruiting |
Enrollment | 48 |
Est. completion date | April 10, 2025 |
Est. primary completion date | April 10, 2025 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years and older |
Eligibility | Inclusion Criteria: - aged = 18 years - American society of anesthesiology (ASA) physical status of I-III - scheduled for elective thoracotomy Exclusion Criteria: - Contraindication to thoracic paravertebral block as coagulopathy or local anesthetic allergy. - Pregnancy - History of cardiovascular and gastro-esophageal surgery - Preexisting pain syndrome or psychological disorders - Severe hepatic, cardiovascular, or renal disorders - Allergy to calcitonin - Patients who will be re-operated and who will report infections |
Country | Name | City | State |
---|---|---|---|
Egypt | Tanta University Hospitals | Tanta | Gharbiya |
Lead Sponsor | Collaborator |
---|---|
Tanta University |
Egypt,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | morphine consumption | total morphine consumption in the first 24 hours after surgery | from the end of surgery until the end of the first postoperative day | |
Secondary | numerical rating scale scores | A 0-10 cm numerical rating scale ( 0 means no pain and 10 means the worst pain) at coughing and at rest will be assessed by an investigator during the first and second day post operation | from arrival to the post-anesthesia care unit until 48 hour after surgery. | |
Secondary | incidence of chronic pain | chronic pain at 3 and 6 months after surgery | 3 months and 6 months after surgery | |
Secondary | Side effects | hypotension, postoperative nausea and vomiting | first postoperative day |
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