Erector Spinae Plane, Paravertebral Versus Intercostal Nerve Block for VATS Surgery

Thoracic Clinical Trial

Official title:

Erector Spinae Plane, Paravertebral Versus Intercostal Nerve Block for VATS Surgery

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05091398
• Other study ID #: 34779/7/21
• Status: Completed
• Phase: N/A
• Start date: November 5, 2021
• Est. completion date: January 10, 2022

Study information

• Verified date: January 2022
• Source: Tanta University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The optimal analgesia method in video-assisted thoracoscopic surgery (VATS) remains controversial. 105 patients scheduled to undergo video-assisted thoracic surgery under general anesthesia will be included. Patients will be randomly allocated to receive ultrasound-guided ESP blocks on T4 and T6 levels (Group ESPB, n = 35),PVB (Group PVB, n = 35) after the anesthesia induction and turning the patient in the lateral position or (Group ICNB, n=35) with 30 mL 0.5% bupivacaine +50 µ adrenaline will be injected by the surgeon through the thoracoscope .

Description:

Standard general anesthesia was applied Patients will be randomly allocated to receive single shot of ESP blocks (Group ESPB), Paravertebral blocks (Group PVB) or (Group ICNB )at T4 and T6 levels according to a random number list that will be generated by a computer and will be stored in sealed envelopes. An independent experienced anesthesiologist will perform the first two blocks or surgeon will perform the third one through the thoracoscope according to the random number. The study coordinator, attending anesthesiologist, data collection resident and the patients will be all blinded to the treatment group assignment. All blocks will be applied on patient's back in a lateral position. Postoperative analgesia regimen consisted of a continuous infusion of iv iboprofen and morphine as a second rescue drug. Demographic data, past medical history, surgical and anesthetic data will be documented. Postoperative pain scores, consumption of analgesia and quality of recovery will be recorded to evaluate the analgesic effect.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 105
• Est. completion date: January 10, 2022
• Est. primary completion date: January 10, 2022
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 75 Years

Eligibility

Inclusion Criteria:

• ASA I and II patients
• Thoracic surgery

Exclusion Criteria:

• Coagulation defect

Related Conditions & MeSH terms

• Thoracic

Intervention

Other:
• Regional analgesia of thoracic surgical patients
ultrasound-guided erector spinae block on T4 and T6 levels ,paravertebral block or intercostal nerve block after the anesthesia induction and turning the patient in the lateral position with 30 mL 0.5% bupivacaine +50 µ adrenaline will be injected by the surgeon through the thoracoscope .

Locations

Country	Name	City	State
Egypt	Mona Mohamed Mogahed	Tanta	Elgharbia

Sponsors (1)

Lead Sponsor	Collaborator
Tanta University

Country where clinical trial is conducted

Egypt, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	end tidal sevoflurane	intraoperative end tidal sevoflurane	150 minutes
Secondary	Blood pressure	Intraoperative blood pressure in mmHg	150 minutes