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Thoracic Injuries clinical trials

View clinical trials related to Thoracic Injuries.

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NCT ID: NCT06316375 Not yet recruiting - Clinical trials for Blunt Injury of Thorax

STUMBL Score as a Risk Stratification Tool for Management of Blunt Chest Trauma Patients

Start date: April 1, 2024
Phase:
Study type: Observational

The aim of this study is to assess validity of the STUMBL score in EGYPT for complications of blunt chest trauma without multi-trauma and immediate life-threatening injuries and identify patients at risk of in- hospital mortality or ICU admission and predict survival in both Assiut & Suez Canal University Hospitals.

NCT ID: NCT06264856 Suspended - Chest Trauma Clinical Trials

Bronchoscopy for Thoracic Trauma Patients

Start date: December 1, 2024
Phase: N/A
Study type: Interventional

The study aims to evaluate the effectiveness of bronchoscopic sputum suction in patients with severe thoracic illness-induced respiratory failure. The study will compare the outcomes of patients who receive bronchoscopic sputum suction versus blind negative pressure aspiration for sputum removal. The study will measure baseline data, postoperative blood gas conditions, and clinical parameters, such as time of invasive ventilation, total time of ventilation, hospital stay, weaning success rate, reintubation rate, ventilator-associated pneumonia incidence, and fatality rate. The study aims to determine whether bronchoscopy-assisted sputum removal is superior to blind negative pressure aspiration in improving patient outcomes.

NCT ID: NCT06236113 Completed - Clinical trials for Blunt Injury of Thorax

Low Dose Ketamine for Blunt Thoracic Trauma

Start date: October 1, 2021
Phase: Phase 4
Study type: Interventional

The goal of this Randomized controlled double-blinded trial is to compare the addition of a ketamine infusion to placebo, when added to standard care in adult blunt trauma patients with multiple rib fractures. The main question it aims to answer are: • addition of low dose ketamine infusion (LDKI) decreases narcotic use • does LDKI impact pulmonary complications, readmission, or hospital length of stay Participants will receive usual standard of care with up to 48 hours of LDKI or placebo. If there is a comparison group: Researchers will compare infusion of a saline infusion to LDKI to see if LDKI decreases need for narcotic analgesics use.

NCT ID: NCT06078254 Not yet recruiting - Chest Trauma Clinical Trials

Senstivity and Specificity of Lung Ultrasound for Early Detection of ARDS in Patients With Chest Trauma

Start date: October 2023
Phase:
Study type: Observational

The aim of this study is to evaluate the accuracy, sensitivity and specificity of lung ultrasound in early detection of ARDS and Pneumonia in comparison to CT chest in patients with chest trauma. Also, we aim at finding any pulmonary complications and its correlation to development of ARDS and pneumonia in patients with chest trauma.

NCT ID: NCT06072339 Recruiting - Clinical trials for Non-invasive Ventilation

Optimization of Positive End Expiratory Pressure by Use of Pulmonary Ultrasound for Patients With Blunt Chest Trauma Treated by Non-Invasive Ventilation (Opti-PEP).

Opti-PEP
Start date: November 19, 2023
Phase: N/A
Study type: Interventional

This is an open-label, randomized controlled study comparing two non-invasive ventilation initiation strategies.Patients may be included if they present with acute respiratory failure related to blunt chest trauma.The intervention group will benefit from the use by the physiotherapist of pulmonary ultrasound for the adjustment of Positive End Expiratory Pressure (PEEP) during the 1st session. The conventional group will benefit from the non-invasive ventilation according to the current care.

NCT ID: NCT06003595 Completed - Rib Fractures Clinical Trials

Long-term Outcome After Removal of Rib Stabilization Hardware in Patients With Blunt Chest Trauma

REMOVE
Start date: August 4, 2023
Phase:
Study type: Observational

The main study objective is to evaluate the long-term outcome in a prospective follow-up visit of patients who underwent hardware removal after surgical stabilization of rib fractures (SSRF) after a blunt chest trauma .

NCT ID: NCT05991570 Not yet recruiting - Thoracic Injury Clinical Trials

Thoracoscopic Exploration in Comparison to Exploratory Thoracotomy in Chest Trauma

Start date: December 30, 2023
Phase: N/A
Study type: Interventional

Video-assisted thoracic surgery has a standard role in diagnosis and therapy in thoracic surgery, In the past, most patients necessitating surgical treatment secondary to chest trauma was exposed to open thoracotomy, which was the most morbid of surgical incisions

NCT ID: NCT05960409 Not yet recruiting - Clinical trials for Chest Trauma Patients

Outcome of Chest Trauma Patients in One Year in Sohag University Hospital

Start date: August 2023
Phase:
Study type: Observational

The history of chest trauma is as old as that of man himself. One of the earliest writings about chest trauma is found in the Edwin Smith Surgical Papyrus, written in 3000 bc. Over the last century, there has been considerable reduction in the mortality of chest trauma owing to improved pre-operative care, availability of positive pressure ventilation, increasing availability of antibiotics, improvement of radiological techniques and improved lung toilets measures etc. Chest trauma implies trauma to any or combination of different thoracic structures, which can be divided into 4 anatomical regions i.e. the chest wall, the pleural space, the lung parenchyma, and the mediastinum. Trauma is one of the top ranking causes of accidental or unnatural deaths. Chest trauma is a significant source of morbidity and mortality worldwide. overall, it accounts for 25%-30% of all trauma related deaths and is implicated in an additional 25% of patients, who died from injuries. In most cases, blunt chest trauma is by far the commonest and road traffic accidents account for 70%-80% of such injuries. Fire-arm injuries, falling from height, blast, stabs, and various acts of violence are the other causative mechanisms.

NCT ID: NCT05920109 Recruiting - Severe Chest Trauma Clinical Trials

EffecT of eARly analGesia With Erector Spinae Plane Block to Reduce Ventilation After Severe Chest Trauma

TARGET
Start date: October 22, 2023
Phase: N/A
Study type: Interventional

Blunt chest trauma is commonly associated with rib fractures and early pain management is a key goal after chest trauma. In spontaneous breathing patients, pain limits coughing efficiency and secretion clearance, thereby potentially leading to progressive atelectasis, loss of functional residual capacity (FRC) and, ultimately, respiratory distress. In patients under mechanical ventilation, pain interacts with the weaning of mechanical ventilation inducing an increase of the duration of invasive ventilation. According to recent French guidelines for chest trauma management, immediate analgesia is initially performed by intravenous multimodal analgesia followed by a thoracic epidural analgesia or a paravertebral block if the pain is not controlled within the first 12 hours. However, these blocks necessitate an experienced anaesthesiologist, are at risk of severe complications and are contraindicated in case of post-traumatic coagulopathy. All these considerations limit their indication in the trauma bay. The erector spinae plane (ESP) block is an easy to perform, ultrasound guided, regional anaesthesia for pain management after thoracic surgery. This block can be made continuously with a dedicated catheter for a continuous infusion of local anaesthetic drug with boli. The ESP block is performed by depositing the local anaesthetic in the fascial plane, deeper than the erector spinae muscle at the tip of the transverse process of the vertebra. This block is less invasive with fewer contraindications as compared to epidural analgesia or paravertebral blocks. After chest trauma, ESP block was associated with an improvement in respiratory capacity in a retrospective study. However, there is no randomised control trial assessing ESP efficacy. Our hypothesis is that early continuous ESP block in the trauma bay decreases the number of days with invasive and/or non-invasive ventilation after chest trauma.

NCT ID: NCT05886946 Not yet recruiting - Clinical trials for Blunt Injury of Thorax

Abg in Blunt Chest Trauma

Start date: July 1, 2023
Phase:
Study type: Observational

This study aims to determine the value of ABG measurments in patients with blunt chest trauma and its role in prognosis of different outcomes and the results would aid the emergency physicians to speed up the management and reduce the cost of diagnosis