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Clinical Trial Summary

to investigate the efficacy and safety of opioid-free anesthesia for non-small-cell lung cancer resection and its underlying clinical value


Clinical Trial Description

Opioids used to have its irreplaceable role in standard opioid-based anesthesia, yet with the help of hypnotics, local anesthetics, anti-inflammatory drugs, α-2 agonists and epidural techniques, opioid-free anesthesia (OFA) has been proved to be safe and feasible for non-cardiac major surgeries. Opioid-sparing anesthesia (OSA) is encouraged by the needs of enhanced recovery and recommended by the latest guidelines for anesthesia of lung surgery. According to previous studies, both opioid-sparing and opioid-free anesthesia would reduce the incidence of opioid-related adverse events and speed up the postoperative recovery to some extent, yet no studies ever are dedicated to compare these two different techniques. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05063396
Study type Interventional
Source Shanghai Zhongshan Hospital
Contact SHUWEI WANG
Phone +8613564440601
Email [email protected]
Status Recruiting
Phase N/A
Start date July 1, 2021
Completion date December 1, 2025

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