Aortic Elongation and Dissection

Thoracic Aorta Clinical Trial

Official title:

Ascending Aortic Length in Relation to Age and the Occurrence of Type A Aortic Dissection

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02722889
• Other study ID #: 16-4-027
• Status: Completed
• Phase: N/A
• First received: March 7, 2016
• Last updated: March 20, 2017
• Start date: March 2016
• Est. completion date: January 2017

Study information

• Verified date: March 2016
• Source: Maastricht University Medical Center
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Aim of this study is to measure length of the ascending aorta in adults and to investigate the clinical implication of 'elongation' of the aorta.

Description:

Regarding to aortic geometry, attention is often drawn to aortic diameters since an increase in these diameters (e.g. aneurysm) can lead to life-threatening complications such as dissection and/or rupture. In daily practice however (e.g. imaging reports), the investigators often encounter patients with elongation of the ascending aorta. Little is known about the length of the proximal aorta. Furthermore, the clinical implications of an elongated aorta are unknown.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 298
• Est. completion date: January 2017
• Est. primary completion date: December 2016
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Underwent recent (<6 years) contrast-enhanced CT scan which allows for segmentation and assessment of aortic geometry.

Exclusion Criteria:

• Age <18 years old.

• Prior thoracic, cardiac or aortic surgery.

• Genetic disease with cardiac and/or aortic involvement (e.g. Marfan's disease).

• Infectious disease of the aorta.

• Malignant disease with involvement of heart and/or aorta.

Related Conditions & MeSH terms

• Thoracic Aorta

Locations

Country	Name	City	State
Netherlands	Maastricht University Medical Center	Maastricht	Limburg

Sponsors (1)

Lead Sponsor	Collaborator
Maastricht University Medical Center

Country where clinical trial is conducted

Netherlands, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Length of the ascending aorta	Ascending aortic length as measured on computed tomography.	Up to 72 months