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Thermal Burn clinical trials

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NCT ID: NCT03248154 Withdrawn - Wound Clinical Trials

Biofilm Infection in Adults and Children Burn Injury

Start date: January 2017
Phase: N/A
Study type: Interventional

The objective of the study is to analyze the different implications (such as graft loss and conversion of indeterminate depth burns) of biofilm infections in burn patients. Additionally, it also aims at comparing children's resistance to biofilm infection at wound site than adults'. 300 subjects from 3 different age groups will be enrolled in 3 arms.

NCT ID: NCT03148977 Terminated - Burns Clinical Trials

Evaluating MMPs in Burns

Start date: June 9, 2017
Phase:
Study type: Observational

The objective of this study is to determine whether our chemical assay can be used to reliably predict graft take or failure in patients undergoing autologous skin grafting for treatment of acute burn injury.

NCT ID: NCT03077087 Terminated - Thermal Burn Clinical Trials

Single-Stage Integra Reconstruction in Burns

Integra
Start date: April 10, 2017
Phase: N/A
Study type: Interventional

This is a prospective, descriptive, pilot case series involving patients with significant burns who are candidates for reconstruction with Integra®. Subjects would have a small area of the wound would, at the time of excision, have the smallest sheet of thin Integra® (125 cm2) placed and be immediately autografted with a 3:1 meshed split-thickness skin graft. Of note, 125 cm2 represents approximately 0.7% of an average sized patient's total body surface area, so for even the smallest burns in our proposed trial, this area would represent a small portion of the patient's area of injury. The remaining injury areas would be covered with standard-thickness Integra® only.

NCT ID: NCT02362386 Completed - Thermal Burn Clinical Trials

Feasibility of Obtaining ADRCs From Discarded Thermal Burn Eschar Tissue Using Investigational Celution® System

Start date: June 2015
Phase: N/A
Study type: Observational

The objective of the study is to assess the logistical and biological feasibility of preparing ADRCs from adipose tissue excised during standard-of-care burn wound excision using the Celution® System for autologous, same-day application to the burn wound.