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Thermal Ablation clinical trials

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NCT ID: NCT05962892 Recruiting - Clinical trials for Papillary Thyroid Carcinoma

A Study of Factors Influencing Recurrence After Thermal Ablation of Papillary Thyroid Carcinoma

Start date: February 1, 2024
Phase:
Study type: Observational [Patient Registry]

A prospective cohort of papillary thyroid carcinoma(PTC), patients who received thermal ablation in our hospital since February 2023 was established as the study object. Preoperative and postoperative demographic data, ultrasonography, other relevant laboratory tests, and thyroid disease-related scales such as fatigue, depression, and stress were collected. The influencing factors of PTC recurrence were analyzed.

NCT ID: NCT05726981 Not yet recruiting - Thyroid Nodules Clinical Trials

Ultrasound and Cytological Evaluation 3 Years After Radiofrequency Thermal Ablation of Benign Thyroid Nodules : a Prospective Exploratory Cohort of 180 Nodules

CYTOTHYRAF
Start date: February 2023
Phase: N/A
Study type: Interventional

There is no scientific data on post-thermal ablation cytological aspects, but treated nodules that grow back significantly after a procedure justify a new cytology in order not to ignore a neoplastic process. The EU-TIRADS classification usually used to stratify the risk of cancer (and to justify a fine needle aspiration biopsy) of thyroid nodules is not validated for nodules treated by thermal ablation (TA) (post-RF nodules). However, these nodules often acquire ultrasound criteria of suspicion making it necessary to develop an ultrasound stratification of the risk of malignancy specific to nodules treated by TA. The objective of this work is to describe the ultrasound and cytological aspects of these treated nodules by performing a systematic assessment at 3 years after thermal ablation including systematic neck ultrasound and fine needle aspiration biopsy. Thus, an ultrasound and cytological atlas (Bethesda classification 2017) of nodules treated by thermal ablation will be constituted.

NCT ID: NCT04665609 Not yet recruiting - Clinical trials for Hepatocellular Carcinoma

Thermal Ablation Combined With Anlotinib and TQB2450 Solution for HCC

Start date: March 5, 2021
Phase: Phase 3
Study type: Interventional

In this study, investigators aimed to evaluated the efficacy and safety of microwave ablation combined with anlotinib and TQB2450 Solution in patients with advanced hepatocellular carcinoma. Patients were randomly assigned at a one-to-one ratio to receive microwave ablation plus anlotinib and TQB2450 Solution or microwave ablation plus TQB2450 Solution. Primary end points were objective response rate(ORR). Second end points include overall survival, progression-free survival and disease control rate. Safety was assessed in all patients.