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Haploidentical Hematopoietic Stem Cell Transplantation for Patients With Thalassemia Major

Thalassemia Major Clinical Trial

Official title:
Haploidentical Hematopoietic Stem Cell Transplantation for Patients With Thalassemia Major

Clinical Trial Summary

The purpose of the study is to assess the safety and efficacy of haploidentical hematopoietic stem cell transplantation for patients with thalassemia major.

Clinical Trial Description

The only curative therapy for thalassemia major remains the replacement of the defective erythropoiesis by allogeneic hematopoietic stem cell transplantation(HSCT). However, this option is unavailable to many patients as a result of a lack of compatible donors.Haploidentical transplantation has been certified as a valuable alternative for hematological malignancy patients lacking a well-matched donor, with results comparable matched HLA-identical sibling donors or unrelated donors.The objective of this study is to test the feasibility of haploidentical HSCT for patients with thalassemia major. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03171831
Study type Interventional
Source First Affiliated Hospital of Guangxi Medical University
Contact Yongrong Lai, MD
Phone +86(0771)5356510
Email laiyongrong@hotmail.com
Status Recruiting
Phase Phase 4
Start date April 1, 2017
Completion date April 1, 2022
View Details
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